← Back to Search

Operant Conditioning for ACL Injury

N/A
Waitlist Available
Research Sponsored by University of Michigan
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Have undergone ACL reconstructive surgery
Suffered an acute, complete ACL rupture
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline (before the start of the intervention) and post-intervention (approximately 2 weeks after baseline)
Awards & highlights

Study Summary

This trial will test if operant conditioning can help improve the changes in the nervous system that occur after ACL surgery.

Who is the study for?
This trial is for individuals aged 14-45 who have had ACL reconstructive surgery due to an acute, complete rupture. Participants must be willing to follow the study's procedures. Those pregnant or planning pregnancy, with ear/heart devices, fainting history, contralateral ACL injury, seizures, significant other knee injuries/fractures, recurrent headaches, major contralateral knee surgery, uncontrolled diabetes/hypertension or head metal implants cannot join.Check my eligibility
What is being tested?
The study tests if operant conditioning—a type of mental coaching and encouragement—can improve changes in brain-to-muscle communication after ACL reconstruction. Participants will either receive this mental coaching or be part of a control group without it.See study design
What are the potential side effects?
Since the intervention involves non-invasive mental coaching techniques rather than medication or surgery, no direct physical side effects are expected from the operant conditioning itself.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You have had surgery to repair a torn ACL.
Select...
You have recently experienced a complete tear in your ACL (a ligament in your knee).

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline (before the start of the intervention) and post-intervention (approximately 2 weeks after baseline)
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline (before the start of the intervention) and post-intervention (approximately 2 weeks after baseline) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Changes in corticospinal excitability
Other outcome measures
Changes in quadriceps strength
Changes in quadriceps voluntary activation

Trial Design

2Treatment groups
Experimental Treatment
Group I: Operant ConditioningExperimental Treatment1 Intervention
Motor evoked responses will be elicited along with operant conditioning training for about 2 weeks
Group II: ControlExperimental Treatment1 Intervention
Motor evoked responses will be elicited without operant conditioning training for about 2 weeks
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Operant Conditioning
2022
N/A
~30
Control
2011
Completed Phase 4
~15780

Find a Location

Who is running the clinical trial?

University of MichiganLead Sponsor
1,780 Previous Clinical Trials
6,364,513 Total Patients Enrolled
5 Trials studying Anterior Cruciate Ligament Injury
282 Patients Enrolled for Anterior Cruciate Ligament Injury

Media Library

Operant Conditioning Clinical Trial Eligibility Overview. Trial Name: NCT05519345 — N/A
Anterior Cruciate Ligament Injury Research Study Groups: Operant Conditioning, Control
Anterior Cruciate Ligament Injury Clinical Trial 2023: Operant Conditioning Highlights & Side Effects. Trial Name: NCT05519345 — N/A
Operant Conditioning 2023 Treatment Timeline for Medical Study. Trial Name: NCT05519345 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many members have been recruited for this clinical trial thus far?

"Affirmative. According to the information on clinicaltrials.gov, this research project is actively seeking volunteers and was initially published on December 1st 2022 with a recent update from October 24th 2022. A total of 20 people are required for participation at one site."

Answered by AI

Are there certain prerequisites individuals need to satisfy in order to join this experiment?

"The scope of this trial is limited to individuals aged 14-45 years with a confirmed anterior cruciate ligament tear. The following requirements must be met for participation: undergone ACL reconstructive surgery, acute and complete rupture of the ACL, readiness to conform to testing protocol as well as subsequent follow-up visits."

Answered by AI

Is the recruitment phase of this clinical trial still underway?

"Affirmative. Clinicaltrials.gov data suggests that this clinical trial is actively recruiting individuals, having been posted on December 1st 2022 and edited October 24th 2022. For the purpose of the study, 20 patients need to be identified from a single medical centre."

Answered by AI

Does the eligibility criteria for this trial encompass individuals beyond 40 years of age?

"The age range for enrollment in this trial is bounded between 14 and 45 years old."

Answered by AI
~10 spots leftby Mar 2025