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Behavioral Activation for Anhedonia

N/A
Waitlist Available
Led By Christian A Webb, Ph.D.
Research Sponsored by Mclean Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Right handed
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from pre-treatment (baseline) to post-treatment (12 weeks)
Awards & highlights

Study Summary

This trial will examine whether behavioral activation, a treatment targeting anhedonia, can help improve symptoms of depression in adolescents.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You are right-handed.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from pre-treatment (baseline) to post-treatment (12 weeks)
This trial's timeline: 3 weeks for screening, Varies for treatment, and change from pre-treatment (baseline) to post-treatment (12 weeks) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in anhedonic (SHAPS) symptoms
Change in brain (striatal and medial PFC) activation during a monetary reward gambling task
Change in performance (reward learning) on a probabilistic reward learning computer task

Trial Design

1Treatment groups
Experimental Treatment
Group I: Behavioral ActivationExperimental Treatment1 Intervention
12 weeks (1 50-min session per week) of Behavioral Activation for the anhedonic adolescents. Behavioral Activation is a psychosocial treatment for depression focused on gradually re-engaging patients with sources of reinforcement and reward in their environment (e.g., increasing activites and interpersonal interactions). In contrast to Cognitive Behavioral Therapy, and as the name implies, Behavioral Activation focuses on behavioral strategies to improve mood and places little emphasis on cognitive restructuring techniques.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Behavioral Activation
2013
Completed Phase 3
~2980

Find a Location

Who is running the clinical trial?

Mclean HospitalLead Sponsor
212 Previous Clinical Trials
21,703 Total Patients Enrolled
5 Trials studying Anhedonia
743 Patients Enrolled for Anhedonia
Christian A Webb, Ph.D.Principal InvestigatorMcLean Hospital & McLean Hospital

Media Library

Behavioral Activation Clinical Trial Eligibility Overview. Trial Name: NCT02498925 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this research trial accept participants above the age of 45?

"Aspiring enrollees in this research must be between 13 and 18 years old."

Answered by AI

To what extent is participation in this medical experiment widespread?

"Affirmative. Clinicaltrials.gov conveys that this trial, which began recruiting on December 1st 2015, is actively in search of participants. There needs to be a total of 70 patients enrolled at one medical site."

Answered by AI

Are researchers currently recruiting participants for this research endeavor?

"Affirmative. According to clinicaltrials.gov, this trial is currently enrolling patients and was initially advertised on December 1st 2015. The most recent update occurred on April 4th 2022. A total of 70 participants are needed for the study at a single site."

Answered by AI

What are the eligibility criteria for enrollment in this trial?

"Access to the trial is restricted to teenagers between 13 and 18 years old with anhedonia. 70 adolescents will be recruited in total."

Answered by AI
~9 spots leftby Mar 2025