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Iron repletion for Iron Deficiency (DIDS Trial)
N/A
Waitlist Available
Led By Eldad Hod, MD
Research Sponsored by Columbia University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
18-75 years old;
healthy (by self report);
Timeline
Screening 3 weeks
Treatment Varies
Follow Up performed 42 days after blood donation
Awards & highlights
DIDS Trial Summary
Primary Hypothesis The 24-hour post-transfusion RBC recovery of units obtained from donors exhibiting iron-deficient erythropoiesis will not meet FDA standards for clinical use. The 24-hour post-transfusion RBC recovery of units obtained after intravenous iron repletion will improve significantly and will meet FDA standards for clinical use.
Eligible Conditions
- Iron Deficiency
DIDS Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowDIDS Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ performed 42 days after blood donation
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~performed 42 days after blood donation
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
51-Chromium 24-hour post-transfusion RBC recovery of units
Secondary outcome measures
Beck Anxiety Inventory (BAI) score
Beck Depression Inventory (BDI) II score
Global Fatigue Index (GFI) score
+17 moreDIDS Trial Design
2Treatment groups
Active Control
Placebo Group
Group I: Iron repletionActive Control4 Interventions
Subjects will donate blood donation and undergo 24-hour PTR and receive IV iron-dextran. After 5 months, subjects will donate blood again, receive IV saline and undergo 24-hour PTR.
Group II: PlaceboPlacebo Group4 Interventions
Subjects will donate blood donation and undergo 24-hour PTR and receive IV saline. After 5 months, subjects will donate blood again, receive IV iron-dextran and undergo 24-hour PTR.
Find a Location
Who is running the clinical trial?
Columbia UniversityLead Sponsor
1,426 Previous Clinical Trials
2,473,323 Total Patients Enrolled
New York Blood CenterOTHER
23 Previous Clinical Trials
26,609 Total Patients Enrolled
National Heart, Lung, and Blood Institute (NHLBI)NIH
3,818 Previous Clinical Trials
47,295,087 Total Patients Enrolled
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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