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Behavioral Intervention

Gamification for Alzheimer's Disease

N/A
Waitlist Available
Led By Ryan Greysen, MD, MHS, MA
Research Sponsored by University of Pennsylvania
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
own a smartphone
be enrolled in GeneMatch
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline to 12 week intervention period (weeks 1 - 12)
Awards & highlights

Study Summary

This trial will test if giving people social incentives (like a game) to walk more every day can help prevent Alzheimer's Disease and Related Dementias.

Eligible Conditions
  • Alzheimer's Disease
  • Dementia

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline to 12 week intervention period (weeks 1 - 12)
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to 12 week intervention period (weeks 1 - 12) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Mean Daily Steps From the Baseline Period to the End of the 12 Week Intervention Period.
Secondary outcome measures
Change in Mean Daily Step Counts During the 6 Week Follow-up Period After the End of the Intervention Period Tracked by Fitbit Inspire Device.
Other outcome measures
Change in Moderate-vigorous Physical Activity (MVPA) Minutes During the Baseline and Follow-up Period (Weeks 13-18).
Change in Moderate-vigorous Physical Activity Minutes (MVPA) During the Start of the Intervention Period Compared to Baseline Period.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: GamificationExperimental Treatment1 Intervention
Intervention participants will receive a wearable device (e.g. FitBit) and will enter a game designed with behavioral economics concepts to address predictable barriers to behavior change during a 12-week intervention period. At the end of the 12 week intervention period, participants will enter a 6 week follow-up period during which interventions will cease but passive data collection of step counts will continue. Participants will also complete milestones within the study, such as the cognition and function assessment during weeks 1- 2, and 15-16. Participants will complete an end-of-study questionnaire on their experience with the wearable device and intervention design.
Group II: ControlActive Control1 Intervention
Participants will receive a wearable device (e.g. FitBit) but no other interventions during the intervention or follow-up periods.Participants will also complete milestones within the study, such as the cognition and function assessment during weeks 1- 2, and 15-16. Participants will complete an end-of-study questionnaire on their experience with the wearable device and time in the study.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Gamification
2019
Completed Phase 3
~2230

Find a Location

Who is running the clinical trial?

University of PennsylvaniaLead Sponsor
1,992 Previous Clinical Trials
42,875,120 Total Patients Enrolled
National Institute on Aging (NIA)NIH
1,655 Previous Clinical Trials
28,003,930 Total Patients Enrolled
Ryan Greysen, MD, MHS, MAPrincipal InvestigatorUniversity of Pennsylvania
4 Previous Clinical Trials
717 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Do individuals who are 75 and younger fulfill the criteria for this investigation?

"This experiment only permits individuals aged 55 to 75. On the contrary, there are a total of 34 trials targeting younger people and 755 studies for elderly patients."

Answered by AI

Is enrollment underway for this experimental program?

"The information hosted on clinicaltrials.gov suggests that this particular research is not actively recruiting participants. Initially posted in early November 2021 and most recently edited a year later, it appears as though the trial has paused enrolling patients; however, there are 767 other studies currently looking to recruit individuals at present."

Answered by AI

Is there an opportunity for me to contribute as a participant in this medical study?

"This research initiative is seeking 90 individuals, aged fifty-five to seventy-five years old with diagnosed dementia. Those wishing to take part must possess a smartphone and be registered in GeneMatch."

Answered by AI
~72 spots leftby Mar 2025