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Creatine Monohydrate for Alzheimer's Disease (CABA Trial)
CABA Trial Summary
This trial will test whether creatine monohydrate can help treat Alzheimer's disease.
CABA Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowCABA Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.CABA Trial Design
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Who is running the clinical trial?
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- My cognitive issues are due to Alzheimer's disease.I am between 60 and 90 years old.I have kidney or liver problems.My medication has been the same for the last 30 days.I have a condition that is causing my brain or nerves to deteriorate over time.I do not speak English.I cannot perform strength tests.I have diabetes needing insulin, had cancer treatment in the last 5 years, or a recent heart event.
- Group 1: Creatine Monohydrate Arm
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many subjects are enrolled in this research project?
"That is correct. The information available on clinicaltrials.gov suggests that the trial is still recruiting patients. 20 individuals are needed from 1 site, and the posting date was November 30th, 2020 with the most recent update being on November 1st, 2020."
Are people of all ages being accepted for this trial, or are there age restrictions?
"As long as they are between 60 and 90 years old, patients of any age can participate in this clinical trial."
Are patients currently being signed up for this research study?
"That is correct. The online clinicaltrials.gov registry currently lists this study as recruiting patients. 20 participants are needed for the trial which is set to take place at a single location. This particular research project was first posted on 11/30/2022 and received its most recent update on 11/1/2022."
Who does this research project require for participation?
"20 individuals with Alzheimer's disease will be enrolled in this trial. The participants must meet the following requirements: They must have a diagnosis of cognitive impairment due to Alzheimer's disease, they must have a study partner who agrees to cooperate, they must speak English as their primary language, they must be between the ages 60 and 90, they must have been on stable medication for at least 30 days prior to enrolling in the study,, and their body mass index (BMI) must be greater than or equal to 20.0kg/m2."
Why was this particular clinical trial designed and what are its goals?
"The primary goal of this 8-week clinical trial is to study the effect of the experimental medication on blood creatine levels. Additionally, changes in peripheral mitochondrial respiration (oxygen consumption), muscle strength, and cognition will be measured as secondary outcomes."
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