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Simulated Altitude for Altitude Hypoxia

N/A
Waitlist Available
Led By Courtney M Wheatley
Research Sponsored by Mayo Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and 6- and 8-week

Summary

This trialwill investigate the effects of altitude and exercise intensity on healthy people. It may help us find better ways to exercise at high altitudes.

Eligible Conditions
  • Altitude Hypoxia

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and 6- and 8-week
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and 6- and 8-week for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Secondary study objectives
Change in cycling performance at altitude
Change in peak VO2

Trial Design

4Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: Effect of saturation of oxygen training in simulated altitudeExperimental Treatment1 Intervention
Participants will exercise in simulated altitude start at a minimum of 2,000ft and will increase to no greater than 16,400ft with each visit. The increase will be in accordance to maintaining 40-60% of max work rate during room air work rate and based upon saturation of oxygen of between 70-80%.
Group II: Effect of heart rate training in simulated altitudeExperimental Treatment1 Intervention
Participants will exercise in simulated altitude start at a minimum of 2,000ft and will increase to no greater than 16,400ft with each visit. The increase will be in accordance to maintaining \>65% max heart rate during room air based maximal peak work.
Group III: Effect of optimized training in simulated altitudeActive Control1 Intervention
Participants will perform the more beneficial intervention (heart rate or saturation of oxygen training) to evaluate whether it improves elite athlete's training status at altitude.
Group IV: Effect of placebo training in non-simulated altitudePlacebo Group1 Intervention
Participants will perform placebo beneficial intervention (heart rate or saturation of oxygen training) to evaluate whether the optimized protocol truely improves elite athlete's training status at altitude.

Find a Location

Who is running the clinical trial?

Mayo ClinicLead Sponsor
3,307 Previous Clinical Trials
2,962,328 Total Patients Enrolled
Courtney M WheatleyPrincipal InvestigatorMayo Clinic
~11 spots leftby Oct 2025
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