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Behavioral Intervention

Cognitive Bias Modification for Intermittent Explosive Disorder

N/A
Waitlist Available
Research Sponsored by Temple University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up preatment, post-treatment (4 weeks later) and 1-month follow-up. total of 2 months
Awards & highlights

Study Summary

This trial will test a computer program to see if it can help people with aggression problems by changing the way they pay attention and interpret things.

Eligible Conditions
  • Intermittent Explosive Disorder

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~pretreatment, posttreatment (4 weeks later) and 1-month follow-up. total of 2 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and pretreatment, posttreatment (4 weeks later) and 1-month follow-up. total of 2 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Social Information Processing from pretreatment to end of treatment (4 weeks later) and 1-month follow-up
Change in a Aggression from pretreatment to end of treatment (4 weeks later) and 1-month follow-up
Change in a Anger from pretreatment to end of treatment (4 weeks later) and 1-month follow-up
Secondary outcome measures
Change in Emotion Regulation from pretreatment to end of treatment (4 weeks later) and 1-month follow-up
Change in IED diagnosis from pretreatment to end of treatment (4 weeks later) and 1-month follow-up

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Bias ModificationExperimental Treatment1 Intervention
Attention (ATT) and interpretation (ITT) bias training. Participants complete the ATT and ITT tasks twice per week for four weeks. The ATT trains attention toward neutral stimuli and away from negative stimuli. On trials with one neutral and one threat word, the probe will always follow the location of the neutral word. Therefore, there is a contingency between the valence of the word and the location of the probe. Participants will be asked to indicate which type of probe had appeared in each trial by pressing a corresponding button as rapidly and accurately as possible. The ITT trains participants to make benign (vs. threatening) interpretations of socially-ambiguous scenarios. For each trial, a word suggesting a socially threatening or benign interpretation is presented then replaced by a sentence describing a socially-ambiguous scenario. Participants indicate if they thought the word and sentence were related. Participants will receive corrective feedback after each trial.
Group II: Control ConditionPlacebo Group1 Intervention
A combination of attention (ATT-C) and interpretation (ITT-C) control tasks These tasks are identical to the experimental tasks (ATT and ITT) with the exceptions that: ATT-C: It is designed to train attention toward neither neutral nor the threat stimuli. This will be achieved by having an equal number of probes follow the location of the threatening word and the neutral word. ITT-C: It is not designed to train benign interpretations of ambiguous social scenarios. Thus, no feedback will be given during the inter-trial interval, rather participants will see a blank screen between trials. Participants will complete both the ATT-C and ITT-C tasks twice per week for four weeks, totaling to eight experimental sessions.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Cognitive Bias Modification
2021
N/A
~310

Find a Location

Who is running the clinical trial?

Temple UniversityLead Sponsor
294 Previous Clinical Trials
81,753 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research experiment still recruiting participants?

"According to clinicaltrials.gov, this medical investigation is no longer seeking volunteers; however, the trial was initially posted on May 1st 2021 and last updated in March 25th of that same year. Thankfully, there are 68 other studies currently recruiting patients across multiple sites."

Answered by AI

Does this clinical research accept participants who are over the age of sixty?

"This clinical trial is reserved for patients between the ages of 18 and 55. For those younger or older, there are 17 studies available for minors and 51 trials designed specifically for individuals 65 years old or above."

Answered by AI

Are any eligibility criteria in place for participants of this experiment?

"Eligibility criteria for this clinical trial is intermittent explosive disorder and an age range of 18 to 55 years old. 45 total individuals are needed to be recruited into the study."

Answered by AI
~12 spots leftby Mar 2025