← Back to Search

Other

CNAP for ARDS (CNAP in ARDS Trial)

N/A
Recruiting
Led By Laurent Brochard, MD
Research Sponsored by The Hospital for Sick Children
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patients with moderate to severe ARDS as per the Berlin definition (PaO2/FiO2 ≤200mmHg)
Patients with absence of any significant cardiopulmonary disease
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 30 min
Awards & highlights

CNAP in ARDS Trial Summary

This trial is testing a device that applies continuous negative abdominal pressure to patients with ARDS, in order to see if it is effective.

Who is the study for?
This trial is for adults over 18 with moderate to severe ARDS, defined by specific oxygenation criteria. They shouldn't have significant heart or lung diseases apart from ARDS. People can't join if they have conditions that prevent the use of CNAP or EIT electrodes, severe liver issues, extreme respiratory acidosis, very high carbon dioxide levels in their blood, or advanced COPD.Check my eligibility
What is being tested?
The trial is testing a device that applies continuous negative pressure to the abdomen in patients suffering from ARDS. The goal is to see if this device helps improve breathing and oxygen levels in these critically ill patients.See study design
What are the potential side effects?
Potential side effects may include discomfort due to the negative pressure application, skin irritation where electrodes are placed for monitoring, and possible worsening of underlying conditions due to changes in abdominal pressure.

CNAP in ARDS Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
My lung condition is severe, fitting the Berlin definition.
Select...
I do not have any major heart or lung diseases.
Select...
I am 18 years old or older.

CNAP in ARDS Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~30 min
This trial's timeline: 3 weeks for screening, Varies for treatment, and 30 min for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Hypotension (SAFETY)
Oxygen saturation measurement
Oxygenation (SAFETY)
Secondary outcome measures
Oxygenation (EFFICACY)

CNAP in ARDS Trial Design

1Treatment groups
Experimental Treatment
Group I: Single armExperimental Treatment1 Intervention
Patients with ARDS will be placed inside of a Continuous Negative Abdominal Pressure Device. Negative pressure will be applied to the abdomen as an adjunct to positive pressure ventilation
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
CNAP
2011
N/A
~50

Find a Location

Who is running the clinical trial?

The Hospital for Sick ChildrenLead Sponsor
683 Previous Clinical Trials
6,944,954 Total Patients Enrolled
Unity Health TorontoOTHER
535 Previous Clinical Trials
447,043 Total Patients Enrolled
Laurent Brochard, MDPrincipal InvestigatorUnity Health Toronto
11 Previous Clinical Trials
3,604 Total Patients Enrolled

Media Library

CNAP (Other) Clinical Trial Eligibility Overview. Trial Name: NCT03425318 — N/A
Acute Respiratory Distress Syndrome Clinical Trial 2023: CNAP Highlights & Side Effects. Trial Name: NCT03425318 — N/A
Acute Respiratory Distress Syndrome Research Study Groups: Single arm
CNAP (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03425318 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this clinical trial admit seniors aged 65 or older?

"This study is searching for participants who are between 18 and 80 years old."

Answered by AI

What is the total cohort size for this research endeavor?

"Affirmative. Clinicaltrials.gov verifies that enlistment is still open for this medical research, which was posted on April 1st 2019 and most recently modified on September 10th 2021. The clinical trial is recruiting 40 subjects from a single centre of operation."

Answered by AI

Is the process of enrolling patients for this experiment ongoing?

"Affirmative. The data hosted on clinicaltrials.gov indicates that this research, which was initially listed on April 1st 2019 is currently enrolling participants. Approximately 40 patients must be enrolled at one medical centre for the trial to proceed."

Answered by AI

Am I eligible to partake in this medical investigation?

"Eligibility for this trial necessitates respiratory distress syndrome and an age between 18 to 80 years old. 40 participants must be recruited in total."

Answered by AI
~5 spots leftby Dec 2024