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Ondansetron for Acute Respiratory Distress Syndrome (DRIVE Trial)
DRIVE Trial Summary
This trial will study the effects of a drug called ondansetron on respiratory drive in patients with acute respiratory distress syndrome (ARDS), with the aim of reducing patient self-inflicted lung injury (P-SILI) in ARDS.
DRIVE Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowDRIVE Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.DRIVE Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
What adverse effects might be experienced from Ondansetron Injection?
"Ondansetron Injection has been evaluated to a score of 3 as it is currently approved, which falls under the parameters of Phase 4 trials."
Is the scope of this experiment restricted to those aged thirty or younger?
"This trial is accessible to individuals between 18 to 75 years of age. As an alternative, those below or above this range can look into 410 trials for minors and 1091 clinical research studies open to seniors."
Are there opportunities for me to participate in this experiment?
"This clinical trial seeks to enrol 10 participants suffering from Respiratory Distress Syndrome, aged between 18 and 75. Notably, applicants must fulfil the following criteria: remain on mechanical ventilation for 24 hours; be currently connected or plan to be connected to Pressure Support Ventilation within a day; have an oxygen-to-fraction ratio of PaO2/FiO2 lower than 300; display chest imaging with bilateral opacity that cannot fully be explained by effusions, lung collapse or nodules appearing in seven days since their last known illness episode; and need to have been mechanically ventilated for more than 48 hours."
Are any openings available for potential participants in this clinical trial?
"The data located on clinicaltrials.gov suggests that this experiment is not actively recruiting participants at the moment, as it was first posted in November 25th 2022 and last updated 24 hours prior to writing this answer. Nonetheless, there are a plethora of other medical trials open for enrollment presently-- 1,527 total."
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