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Corticosteroid

Glucocorticoid Administration for Wrist Fractures

Phase 4
Recruiting
Led By Liam Dwyer, MD
Research Sponsored by C. Liam Dwyer
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 0-12 months
Awards & highlights

Study Summary

This trial will compare patients who receive glucocorticoid injections to those who don't, to see if there's a difference in how well they recover from a broken wrist.

Eligible Conditions
  • Distal Radius Fracture

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~0-12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 0-12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
PROMIS Pain Interference
PROMIS Self-Efficacy Manage Symptoms
PROMIS Upper Extremity
+2 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Glucocorticoid (GC) groupExperimental Treatment2 Interventions
Intraoperative: Single intraoperative dose of 10 mg intravenous dexamethasone Postoperative: A 6-day oral methylprednisolone (oral GC) taper course. The oral GC taper course begins on the day of surgery and includes 24mg on day 1, 20mg on day 2, 16mg on day 3, 12mg on day 4, 8mg on day 5, and 4mg on day 6
Group II: Control (non-GC) groupActive Control1 Intervention
No GC administration
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Methylprednisolone
FDA approved
Dexamethasone
FDA approved

Find a Location

Who is running the clinical trial?

C. Liam DwyerLead Sponsor
Liam Dwyer, MDPrincipal Investigator - Geisinger Clinic
Geisinger Clinic

Media Library

Dexamethasone (Corticosteroid) Clinical Trial Eligibility Overview. Trial Name: NCT03898154 — Phase 4
Distal Radius Fracture Research Study Groups: Glucocorticoid (GC) group, Control (non-GC) group
Distal Radius Fracture Clinical Trial 2023: Dexamethasone Highlights & Side Effects. Trial Name: NCT03898154 — Phase 4
Dexamethasone (Corticosteroid) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03898154 — Phase 4

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this clinical investigation soliciting participants currently?

"Absolutely. According to information provided on clinicaltrials.gov, this medical study is actively seeking participants and was initially posted in July of 2019 before receiving its most recent update in December 2022. 200 patients are being recruited from one specialist centre."

Answered by AI

Has Dexamethasone been sanctioned by the FDA?

"The safety of Dexamethasone was assessed to be a 3 out of 3, as Phase 4 trials have been completed and the drug is approved for use."

Answered by AI

What other studies have explored the potential of Dexamethasone in a medical setting?

"Currently, there are 680 clinical trials worldwide employing Dexamethasone. Of these studies, 174 have progressed to Phase 3 status. Although the majority of sites administering this treatment can be found in Duarte, California; 23444 other locations around the world offer patients access to it as well."

Answered by AI

What illnesses is Dexamethasone typically prescribed to address?

"Dexamethasone can be utilised to treat synovitis and a variety of other conditions, including ophthalmia, sympathetic issues, scalp structure irregularities, and branch retinal vein occlusion."

Answered by AI

How many volunteers have been accepted for this experiment?

"Affirmative. According to the data posted on clinicaltrials.gov, this medical investigation is currently seeking candidates for enrollment; it was first published in July 2019 and its most recent update occurred at the start of December 2022. A total of 200 individuals must be recruited from one location."

Answered by AI
~35 spots leftby Mar 2025