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Omega-3 Fatty Acids

1 for Frailty

Phase 4
Waitlist Available
Led By Anne Kenny, MD
Research Sponsored by Donaghue Medical Research Foundation
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Postmenopausal women over 65 years old
Spine or hip bone density T score less than -1
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 3 and 6 months
Awards & highlights

Study Summary

The purpose of this study is to examine the effects of essential fatty acid (EFA) supplementation on bone metabolism and frailty in postmenopausal women. The overall hypothesis is that EFA supplementation, via its immunoregulatory and anti-inflammatory activity, will decrease bone turnover, decrease prostaglandins and cytokines associated with bone metabolism and frailty, and change physical outcome measures associated with frailty in postmenopausal women with low bone mass and frailty.

Eligible Conditions
  • Frailty
  • Osteoporosis

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 3 and 6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 3 and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Bone turnover markers
Secondary outcome measures
Blood pressure and lab work, including lipids, cytokines, prostaglandins, lymphocyte characterization, and EPA/DHA in blood and plasma
Bone Mineral Density
Cognitive status, mood and depression
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: 1Experimental Treatment2 Interventions
Group II: 2Placebo Group2 Interventions
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
DHA/EPA
2006
Completed Phase 3
~4210
Calcium with vitamin D
2003
N/A
~60

Find a Location

Who is running the clinical trial?

University of ConnecticutOTHER
181 Previous Clinical Trials
158,046 Total Patients Enrolled
3 Trials studying Frailty
288 Patients Enrolled for Frailty
Donaghue Medical Research FoundationLead Sponsor
23 Previous Clinical Trials
578,317 Total Patients Enrolled
Anne Kenny, MDPrincipal InvestigatorUniversity of Connecticut Center on Aging
3 Previous Clinical Trials
261 Total Patients Enrolled
2 Trials studying Frailty
239 Patients Enrolled for Frailty

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~8 spots leftby Mar 2025