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Thyroid Hormone Replacement

Levothyroxine Sodium for Hypothyroidism

Phase 4
Waitlist Available
Led By Vijiya Surampudi, MD
Research Sponsored by University of California, Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 weeks
Awards & highlights

Summary

This trial is testing a liquid form of levothyroxine to see if it better manages thyroid function in patients with hypothyroidism who use feeding tubes. These patients often struggle with traditional tablet forms of the medication. The liquid form is expected to be absorbed more consistently, potentially improving their thyroid levels and symptoms. Levothyroxine is a standard therapy for hypothyroidism, and liquid formulations have been shown to provide better absorption and thyroid hormone control compared to tablet forms.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change of TSH
Secondary study objectives
percentage of patients with therapeutic FT3
percentage of patients with therapeutic FT4

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Liquid Levothyroxine ManagementExperimental Treatment1 Intervention
Participants will be treated with dose equivalent regimen through enteral feeding tube
Group II: Standard Levothyroxine ManagementActive Control1 Intervention
Participants will continue with the same regimen
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Levothyroxine
FDA approved

Find a Location

Who is running the clinical trial?

University of California, Los AngelesLead Sponsor
1,557 Previous Clinical Trials
10,263,873 Total Patients Enrolled
Vijiya Surampudi, MDPrincipal InvestigatorUniversity of California, Los Angeles
1 Previous Clinical Trials
150 Total Patients Enrolled
~1 spots leftby Oct 2025
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