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Loop Diuretic

Flexible diuretic regimen for Heart Failure

Phase 4
Recruiting
Led By Stuart Smith, MD
Research Sponsored by Lawson Health Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Prescribed and tolerating furosemide with a minimum daily dose of 40mg oral daily
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 90 days
Awards & highlights

Study Summary

This trial will compare two methods of taking diuretics to treat heart failure and find out which is better for preventing hospital visits and kidney damage.

Eligible Conditions
  • Heart Failure
  • Heart Disease

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You are currently taking furosemide, an oral medication, and can tolerate a minimum daily dose of 40mg.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~90 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 90 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Mortality and morbidity composite outcome
Secondary outcome measures
All-cause Hospitalizations
Heart failure
Kidney Failure, Acute

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Flexible diuretic regimenExperimental Treatment1 Intervention
Variable daily dose of diuretic (furosemide) determined based on a pre-specified weight-based scale.
Group II: Fixed - dose diureticActive Control1 Intervention
Pre-determined, fixed daily dose of diuretic (furosemide)

Find a Location

Who is running the clinical trial?

Lawson Health Research InstituteLead Sponsor
654 Previous Clinical Trials
413,155 Total Patients Enrolled
7 Trials studying Heart Failure
1,802 Patients Enrolled for Heart Failure
Stuart Smith, MDPrincipal InvestigatorWestern University
1 Previous Clinical Trials
100 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the Flexible diuretic regimen considered to be risk-free for patients?

"The safety of the flexible diuretic regimen was rated 3 out of 3, as it has already been approved by the FDA for clinical use."

Answered by AI

How many people have elected to participate in this experiment?

"Affirmative. Clinicaltrials.gov has evidence that this research endeavor, created on January 3rd 2023 and last revised March 9th 2023 is actively recruiting applicants. The trial requires 30 people from 1 medical centre to participate."

Answered by AI

Is there still capacity for participants in this research study?

"Affirmative. According to clinicaltrials.gov, this trial is still enrolling participants and has been doing so since it was posted on the 3rd of January 2023; its last edit being made on March 9th the same year. 30 patients are required between a single location for completion of the research study."

Answered by AI
~14 spots leftby Mar 2025