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Herbal Supplement

Huperzine A for Dementia

Phase 4
Waitlist Available
Led By Prasad R Padala, MD, MS
Research Sponsored by VA Nebraska Western Iowa Health Care System
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
age 19-59
diagnosis of schizophrenia by MINI
Timeline
Screening 3 weeks
Treatment Varies
Follow Up first visit, 4 weeks, 8 weeks
Awards & highlights

Study Summary

Use Huperzine-A, a herbal supplement normally used for treatment of Alzheimer's disease, to potentially improve cognitive dysfunction (memory problems) and functional capacity (ability to perform common daily tasks such as cooking, bathing, telephone, shopping) in people with schizophrenia.

Eligible Conditions
  • Dementia
  • Schizophrenia

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~first visit, 4 weeks, 8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and first visit, 4 weeks, 8 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
MATRICS Consensus Cognitive Battery
Secondary outcome measures
University of California Performance Skills Assessment-Brief (UPSA-B)

Trial Design

1Treatment groups
Experimental Treatment
Group I: Huperzine AExperimental Treatment1 Intervention
200 micrograms (mcg) of HuperzineA taken twice daily.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Huperzine A
FDA approved

Find a Location

Who is running the clinical trial?

American Legion of Iowa FoundationOTHER
VA Nebraska Western Iowa Health Care SystemLead Sponsor
8 Previous Clinical Trials
2,205 Total Patients Enrolled
Prasad R Padala, MD, MSPrincipal InvestigatorVA Office of Research and Development
1 Previous Clinical Trials
14 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~1 spots leftby Mar 2025