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LAIV vs IIV for Flu Protection in Twins (FLU-TW Trial)
FLU-TW Trial Summary
This trial is testing whether LAIV or IIV is better at protecting against the flu in identical and fraternal twins.
FLU-TW Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowFLU-TW Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.FLU-TW Trial Design
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Logistics
Participation is compensated
You will be compensated for participating in this trial.
Who is running the clinical trial?
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- You have had severe, life-threatening reactions to previous flu shots.You have asthma, which means you cannot receive the LAIV4 vaccine.You have a condition that affects your immune system, such as serious liver disease, diabetes requiring insulin treatment, or moderate to severe kidney disease.You are allergic to eggs or any ingredients used in vaccines like gentamicin, gelatin, arginine, or MSG.You have used or plan to use experimental drugs within the 30 days before starting the study.You have a weakened immune system, which can be caused by conditions like HIV infection.You have had Guillain-Barre syndrome in the past.
- Group 1: MZ twins (IIV or LAIV4)
- Group 2: DZ twins (IIV or LAIV4)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are there other examples of medical research using Live attenuated influenza vaccine (LAIV4)?
"Currently, there are 22 clinical trials underway for Live attenuated influenza vaccine (LAIV4), with 1 trial in Phase 3. While some of the studies are based in Stanford, California, there are 28 locations across the United States conducting trials for Live attenuated influenza vaccine (LAIV4)."
Because this research is cutting-edge, are investigators only screening participants who fall within a certain age range?
"Children aged 2 to 20 years old are the only patients that fit the requirements for this particular trial. However, there are 22 other clinical trials that might be more applicable for patients under 18 or over 65."
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