Pharmacogenetic test for Mental Health Disorders

Phase-Based Progress Estimates
Cpl Michael J Crescenz VAMC, Philadelphia, PAMental Health DisordersPharmacogenetic test - DiagnosticTest
18 - 80
All Sexes
What conditions do you have?

Study Summary

This trial is designed to see if PGx testing can help reduce polypharmacy (use of multiple medications) among Veterans with mental illness.

Treatment Effectiveness

Effectiveness Progress

3 of 3
This is further along than 93% of similar trials

Study Objectives

2 Primary · 1 Secondary · Reporting Duration: 12 weeks

12 weeks
12 weeks.
Adverse effects
Symptoms of distress

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Trial Design

2 Treatment Groups

Delayed return of results
1 of 2
Immediate return of results
1 of 2

Active Control

Experimental Treatment

500 Total Participants · 2 Treatment Groups

Primary Treatment: Pharmacogenetic test · No Placebo Group · Phase 4

Immediate return of results
Experimental Group · 1 Intervention: Pharmacogenetic test · Intervention Types: DiagnosticTest
Delayed return of resultsNoIntervention Group · 1 Intervention: Delayed return of results · Intervention Types:
First Studied
Drug Approval Stage
How many patients have taken this drug
Pharmacogenetic test

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 12 weeks

Who is running the clinical trial?

Corporal Michael J. Crescenz VA Medical CenterLead Sponsor
30 Previous Clinical Trials
10,183 Total Patients Enrolled
David Oslin, MDPrincipal InvestigatorCpl Michael J Crescenz VAMC
3 Previous Clinical Trials
3,264 Total Patients Enrolled

Eligibility Criteria

Age 18 - 80 · All Participants · 1 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
- You are between 18 and 80 years old. - You have a score of more than 9 on the PHQ-9 questionnaire. - You are currently taking at least one antidepressant from the Sanford PGx panel and at least one other medication for mental health conditions such as antidepressants, antipsychotics, "mood stabilizers," addiction medications, or benzodiazepines. Medications taken for less than 2 months will not count. - You agree to give a blood sample for genetic testing. - You meet the requirements for the PHASER test according to current guidance. - You agree to give informed consent to participate in the study.

Who else is applying?

What state do they live in?
How old are they?
What site did they apply to?
Cpl Michael J Crescenz VAMC100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%
Why did patients apply to this trial?
  • "I want to try different things to help my mental disorder"
How many prior treatments have patients received?

Frequently Asked Questions

Does this trial accept participants aged 85 or older?

"This study is open to those within the 18-80 age range." - Anonymous Online Contributor

Unverified Answer

How many participants are currently enrolled in this research study?

"Affirmative. The information posted on testifies that this medical trial is presently in search of participants. It was first advertised on June 2nd, 2020 and the last update came through July 6th 2021 with a demand for 500 patients to be recruited from one site." - Anonymous Online Contributor

Unverified Answer

Are there any openings for participants in this medical research?

"Confirming the details on, this medicinal experiment is still recruiting patients. It was initially released to the public on June 2nd 2020 and has been modified as recenty as July 6th 2021." - Anonymous Online Contributor

Unverified Answer

To whom is the opportunity to participate in this experiment available?

"To apply for this medical research, potential participants must have a psychiatric or mood-related disorder and be aged between 18 to 80. To date, approximately 500 individuals have been accepted into the study." - Anonymous Online Contributor

Unverified Answer

Has the FDA authorized Pharmacogenetic testing?

"The safety of pharmacogenetic testing has been well established, so it was awarded a score of 3." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.