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Durvalumab for Cervical Cancer (CALLA Trial)
CALLA Trial Summary
This trial is testing whether adding the drug durvalumab to standard chemoradiotherapy improves treatment in women with locally advanced cervical cancer.
- Cervical Cancer
CALLA Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowCALLA Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2022 Phase 2 trial • 80 Patients • NCT03015129CALLA Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
Are there any specific inclusion criteria for this clinical trial?
"Women who have been diagnosed with locally advanced cervical cancer and are between 18 and 130 years old may be eligible to participate in this clinical trial. Currently, the research team is looking to enroll approximately 770 individuals."
What are the conditions that Durvalumab is approved to treat?
"Durvalumab is frequently used as an initial treatment plan. It is also effective in treating advanced thymoma, testicular cancer, carcinoma, and neuroendocrine disorders."
Are people currently being signed up for this experiment?
"Presently, this study is not enrolling new patients. The trial was initially posted on February 15th, 2019 and was most recently edited on October 13th, 2022. If you are searching for other studies, there are presently 326 trials actively looking for participants with locally advanced cervical cancer and 1437 studies for Durvalumab actively looking for participants."
Has Durvalumab been cleared by the FDA?
"Durvalumab was rated a 3 on Power's safety scale. This is because it is a Phase 3 trial, meaning that there is not just some data supporting its efficacy, but multiple rounds of data supporting its safety."
How many different medical facilities are conducting this research today?
"13 sites are currently enrolling patients for this study. To reduce the burden of travel, patients are encouraged to select the location closest to them from the list of participating cities which include La Jolla, Cleveland and Dallas among others."
Are geriatric patients welcome in this clinical trial?
"This particular study is seeking applicants that are aged 18-130. In comparison, there are 111 trials for those under 18 and 1651 for senior citizens."
What other scientific papers exist on Durvalumab's effectiveness?
"As of right now, there are 1437 ongoing clinical trials investigating Durvalumab. Of these, 420 are in Phase 3. Additionally, these trials for Durvalumab are being conducted in 72908 different locations, with several in Shanghai, China."
How many people total will be included in this experiment?
"As of October 13th, 2022, this particular trial is no longer looking for patients. If you check the clinicaltrials.gov website, you will see that there are currently 1437 studies for Durvalumab and 326 studies for patients with locally advanced cervical cancer."
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