This trial will test the effects of a new medication, CPC, on people with a history of fainting spells brought on by sudden changes in position.
- Vasovagal Syncope
1 Primary · 3 Secondary · Reporting Duration: During tilt table testing (up 35 minutes)
Awards & Highlights
2 Treatment Groups
1 of 2
1 of 2
132 Total Participants · 2 Treatment Groups
Primary Treatment: Tilt Table Test · Has Placebo Group · Phase 2
Who is running the clinical trial?
Age 18 - 50 · All Participants · 1 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
- Bartoletti, A. 2000. “'the Italian Protocol': A Simplified Head-up Tilt Testing Potentiated with Oral Nitroglycerin to Assess Patients with Unexplained Syncope”. Europace. Oxford University Press (OUP). doi:10.1053/eupc.2000.0125.
- Bartoletti A, Alboni P, Ammirati F, Brignole M, Del Rosso A, Foglia Manzillo G, Menozzi C, Raviele A, Sutton R. 'The Italian Protocol': a simplified head-up tilt testing potentiated with oral nitroglycerin to assess patients with unexplained syncope. Europace. 2000 Oct;2(4):339-42. doi: 10.1053/eupc.2000.0125.
- 2021. "The Effect of CPC on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near Syncope". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04972123.
Frequently Asked Questions
What condition does the medication CPC - Capsaicin, Phenylephrine, Caffeine commonly help?
"The symptoms of eye pain and an enlarged pupil can both be alleviated by using a medication that contains capsaicin, phenylephrine, and caffeine." - Anonymous Online Contributor
Has the FDA cleared CPC - Capsaicin, Phenylephrine, Caffeine for use?
"CPC - Capsaicin, Phenylephrine, Caffeine - is currently in Phase 2 of clinical trials. While there is evidence that it is safe, more research needs to be done to support its efficacy." - Anonymous Online Contributor
Would this test be appropriate for somebody who is middle-aged?
"This particular clinical trial has an age range of 18 to 50 for patients who wish to enroll." - Anonymous Online Contributor
Are there any specific inclusion criteria for subjects of this research?
"This trial is looking for 132 participants who have syncope and are between 18-50 years old." - Anonymous Online Contributor
Is this research study still open to new participants?
"That is correct, the online information does show that the medical study is still recruiting individuals. The listing was first put up on July 20th, 2021 and was last updated 30 days ago. The researchers conducting the trial need 132 patients total, and are only looking at one potential site." - Anonymous Online Contributor