← Back to Search

Hormone Therapy

Best Systemic Therapy (BST) + Surgery or Radiation Therapy for Prostate Cancer

Phase 2
Waitlist Available
Led By Brian F. Chapin, MD
Research Sponsored by M.D. Anderson Cancer Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Male patients
18 yrs and older
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 60 days
Awards & highlights

Study Summary

This trial is testing whether adding surgery or radiation to hormone therapy is more effective at controlling prostate cancer.

Eligible Conditions
  • Prostate Cancer

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~60 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 60 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Progression-Free Survival

Trial Design

2Treatment groups
Experimental Treatment
Group I: Best Systemic Therapy (BST) + Surgery or Radiation TherapyExperimental Treatment3 Interventions
Group 2 will receive best systemic therapy (BST) in addition to surgery to remove prostate or radiation therapy to the prostate. Treating physician will decide if surgery or radiation therapy is the best choice. Questionnaire completion at 60 days, 12 weeks, and at end of treatment visit. It should take about 15 minutes to complete. Every 6 months after end-of-treatment visit, patient contacted by phone or e-mail and asked questions about how they are feeling. Each phone call should last about 5 minutes.
Group II: Best Systemic Therapy (BST)Experimental Treatment3 Interventions
Group 1 will continue to receive best systemic therapy (BST). Questionnaire completion at 60 days, 12 weeks, and at end of treatment visit. It should take about 15 minutes to complete. Every 6 months after end-of-treatment visit, patient contacted by phone or e-mail and asked questions about how they are feeling. Each phone call should last about 5 minutes.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Questionnaires
2013
Completed Phase 2
~3030

Find a Location

Who is running the clinical trial?

M.D. Anderson Cancer CenterLead Sponsor
2,958 Previous Clinical Trials
1,798,285 Total Patients Enrolled
95 Trials studying Prostate Cancer
29,560 Patients Enrolled for Prostate Cancer
Brian F. Chapin, MDPrincipal InvestigatorM.D. Anderson Cancer Center

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has the FDA ratified a combination of Best Systemic Therapy (BST) plus Surgery or Radiation Therapy?

"The safety of Best Systemic Therapy (BST) + Surgery or Radiation Therapy has been assessed as a level 2 on our risk scale, as this is only a Phase 2 trial and there is evidence supporting its safety, but none suggesting its efficacy."

Answered by AI

Do you have any open slots in this clinical experiment?

"According to clinicaltrials.gov, this particular trial is not presently enrolling patients. Originally posted on March 18th 2013 and last updated on May 4th 2022, although it does not need volunteers at the moment, there are over 1300 other studies recruiting participants currently."

Answered by AI

In which locales is this investigation currently administered?

"Currently, 4 distinct medical centres are in the process of recruiting patients for this trial. These sites include University of Texas MD Anderson Cancer Center in Houston, Fox Chase Cancer Centre in Philadelphia, and Vancouver Prostate Center in Vancouver alongside a fourth undisclosed location."

Answered by AI
~15 spots leftby Mar 2025