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Alkylating agents

Endoscopic Resection for Paranasal Sinus Cancer

Phase 2
Waitlist Available
Led By Marc Cohen, MD
Research Sponsored by Memorial Sloan Kettering Cancer Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Adenocarcinoma
Carotid involvement
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year
Awards & highlights

Study Summary

This trial is testing a new way to treat large tumors in the sinus or nasal cavity. It involves endoscopic surgery, chemotherapy, and proton-beam radiation therapy.

Eligible Conditions
  • Paranasal Sinus Cancer
  • Nasal Tumor
  • Nasal Cavity Adenocarcinoma

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Local Control Assessment of Unresectable Paranasal Sinus and Nasal Cavity Tumors

Trial Design

1Treatment groups
Experimental Treatment
Group I: Unresectable paranasal sinus/nasal cavity malignancyExperimental Treatment4 Interventions
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
cisplatin and etoposide
2017
Completed Phase 2
~30
Cisplatin
2013
Completed Phase 3
~1940
Adjuvant Proton Radiotherapy
2017
Completed Phase 2
~10
Endoscopic Resection
2017
Completed Phase 2
~10

Find a Location

Who is running the clinical trial?

Memorial Sloan Kettering Cancer CenterLead Sponsor
1,927 Previous Clinical Trials
591,404 Total Patients Enrolled
1 Trials studying Paranasal Sinus Cancer
64 Patients Enrolled for Paranasal Sinus Cancer
Marc Cohen, MDPrincipal InvestigatorMemorial Sloan Kettering Cancer Center
1 Previous Clinical Trials
34 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How is Endoscopic Resection typically employed for medical purposes?

"Endoscopic Resection is often prescribed for patients that have advance directives, yet it can also be beneficial in treating merkel cell cancer, neoplasm metastasis, and prostate cancer."

Answered by AI

How many persons have been recruited for this clinical research?

"This clinical trial is no longer open to volunteers. It was posted on the 1st of September 2017 and last updated 8th July 2022. For those still looking for studies, there are 772 trials related to paranasal sinus cancer actively recruiting and 900 regarding Endoscopic Resection that need participants."

Answered by AI

What is the geographical distribution of locations conducting this research in North America?

"This research opportunity is available in 5 different locations, including Basking Ridge, New york and Harrison. To reduce the burden of travel requirements for participants, it is wise to select a trial site that is closest to you."

Answered by AI

Is this trial actively searching for participants?

"Unfortunately, as displayed on clinicaltrials.gov, this trial has concluded its search for participants and is now closed to new applications. Initially posted in September 2017 with a most recent update July 8th 2022; nevertheless there are 1,672 other medical trials currently searching for patients."

Answered by AI

Has the Endoscopic Resection procedure been validated by the Federal Drug Administration?

"Endoscopic Resection has been given a rating of 2 on the safety scale due to available evidence indicating it is moderately safe, though not yet proven effective."

Answered by AI

Could you elaborate on any prior research which has explored the efficacy of Endoscopic Resection?

"Endoscopic Resection was first explored in 1997, and since then 1274 studies have been completed. At the moment, there are roughly 900 active clinical trials taking place across many sites; a prominent center is located in Basking Ridge, New york."

Answered by AI
~0 spots leftby Mar 2025