Suvorexant for Opioid Use Disorder

"This medical study is seeking volunteers aged between 18 and 70."

"Currently, 14 studies are underway examining Suvorexant. 2 of those have reached Phase 3 status. While the main hub for these trials is located in Silver Spring, Maryland there are 71 other sites across the country participating in this research on a drug therapy intervention."

"Suvorexant was granted a score of 2 on the safety scale, as it is just entering Phase 2 trials and there has yet to be any supporting evidence for its efficacy."

"According to the details published on clinicaltrials.gov, this medical experiment is presently enrolling patients and was first made available on February 1st 2021 with its most recent amendment occurring September 8th 2021."

"The primary goal of this research endeavour, to be evaluated through Sleep efficiency on the eve of hospital release, is opioid abstinence. Secondary objectives include a Weekly sleep questionnaire that involves retrospective self-report over 4 outpatient weeks; Actigraphic assessment of motion with an Actiwatch and scoring software; lastly, Urinary cortisol levels measured in picogram per milliliter (pg/ml) across 24 hours to calculate circadiance rhythm."

"This clinical trial, accessible to individuals aged 18-70 who are experiencing difficulty sleeping, is recruiting 210 participants. Eligibility requirements include meeting DSM-5 criteria for opioid use disorder (of any severity), being a male or non-pregnant female using medically accepted birth control methods during the study period, and completing an opioid detox program on days 1 through 4 of their inpatient stay."

"Affirmative. According to clinicaltrials.gov, this medical trial is actively seeking applicants and was first posted on February 1st 2021 with its most recent update made on September 8th 2021. 210 individuals will be recruited from one particular site for the project's duration."