Muscle5 and TRIM7 for Overweight

Phase-Based Progress Estimates
2
Effectiveness
3
Safety
Michaela Devries-Aboud, Waterloo, Canada
Overweight+2 More
Mixed exercise - Other
Eligibility
18 - 65
All Sexes
What conditions do you have?
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Study Summary

This trial is testing whether a combination of two dietary supplements and exercise can help people lose more weight than exercise alone. The study will also look at whether this combination can improve participants' overall health. Muscle5 and TRIM7 are used to treat overweight people.

Eligible Conditions

  • Overweight
  • Obesity

Treatment Effectiveness

Effectiveness Progress

2 of 3
This is further along than 85% of similar trials

Study Objectives

7 Primary · 12 Secondary · Reporting Duration: baseline 0 weeks ("pre study") to 12 weeks ("post study")

Week 12
Antioxidant capacity change
Appendicular lean mass change
BMI change
Blood lipids change
Bodyweight change
Fat mass change
Health-related quality of life (SF 36)
Inflammation CRP change
Inflammation IL-1 change
Inflammation IL-10 change
Inflammation IL-6 change
Inflammation TNF-alpha change
Insulin sensitivity change
Lean mass change
Lean mass/fat mass (body composition index) change
Lower body strength change
Perceived stress change (Perceived Stress Scale)
Percent body fat change
Sleep quality change (Bergen Insomnia Scale)
Upper body strength change
VO2max change
Waist-to-hip ratio change

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Trial Design

2 Treatment Groups

Muscle5 and TRIM7
1 of 2
Placebo
1 of 2
Active Control
Non-Treatment Group

60 Total Participants · 2 Treatment Groups

Primary Treatment: Muscle5 and TRIM7 · Has Placebo Group · Phase 3

Muscle5 and TRIM7ActiveComparator Group · 2 Interventions: Mixed exercise, Muscle5 and TRIM7 · Intervention Types: Other, DietarySupplement
Placebo
Other
PlaceboComparator Group · 1 Intervention: Mixed exercise · Intervention Types: Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline 0 weeks ("pre study") to 12 weeks ("post study")
Closest Location: Michaela Devries-Aboud · Waterloo, Canada
Photo of ontario 1Photo of ontario 2Photo of ontario 3
N/AFirst Recorded Clinical Trial
1 TrialsResearching Overweight
0 CompletedClinical Trials

Who is running the clinical trial?

University of WaterlooOTHER
108 Previous Clinical Trials
206,134 Total Patients Enrolled
Exerkine CorporationLead Sponsor
Michaela Devries-Aboud, PhDPrincipal InvestigatorKinesiology and Health Sciences, University of Waterloo

Eligibility Criteria

Age 18 - 65 · All Participants · 4 Total Inclusion Criteria

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You have received two doses of the COVID-19 vaccine.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.