← Back to Search

Cancer Vaccine

TLPLDC for Melanoma

Phase 2
Waitlist Available
Research Sponsored by Cancer Insight, LLC
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Eastern Cooperative Oncology Group (ECOG) performance status 0,1 (Appendix D)
AJCC stage III or IV completely resectable melanoma identified before surgery
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24 months
Awards & highlights

Study Summary

This trial is testing a new, personalized vaccine for melanoma that is applicable to all patients. The vaccine uses the patient's own dendritic cells (a type of white blood cell) and tumor cells to create a personalized cancer vaccine.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Disease Free Survival Assessment

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: TreatmentExperimental Treatment1 Intervention
autologous TLPLDC (active vaccine)
Group II: PlaceboPlacebo Group1 Intervention
unloaded YCWP + autologous DC (control)
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
TLPLDC
2015
Completed Phase 2
~190

Find a Location

Who is running the clinical trial?

Cancer Insight, LLCLead Sponsor
9 Previous Clinical Trials
396 Total Patients Enrolled
1 Trials studying Melanoma
26 Patients Enrolled for Melanoma
Elios Therapeutics, LLCIndustry Sponsor
2 Previous Clinical Trials
126 Total Patients Enrolled
1 Trials studying Melanoma
26 Patients Enrolled for Melanoma
George E Peoples, MDStudy DirectorLumaBridge
4 Previous Clinical Trials
255 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~18 spots leftby Mar 2025