This trial is evaluating whether Aerobic Exercise Training (AET) will improve 1 primary outcome and 2 secondary outcomes in patients with Usual Interstitial Pneumonia. Measurement will happen over the course of Baseline, after 10 weeks, after 20 weeks (for crossover group).
This trial requires 60 total participants across 2 different treatment groups
This trial involves 2 different treatments. Aerobic Exercise Training (AET) is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 2 and have already been tested with other people.
"Lung diseases are a diverse group of diseases that involve diseases of the respiratory system including those that cause obstruction of airways and are classified principally on whether the origin of the disease lies with the lungs or elsewhere. Lung diseases can be classified by the location and specific types of lesions that they are most likely to produce. Lung diseases can be classified according to whether their cause lies with infectious agents, autoimmune disorders, neoplastic processes or adverse effects of therapeutic and environmental factors. The following subsections describe a sample of the lung diseases classified as part of these categories.\n\nLung diseases can be either "localised" or "generalised"." - Anonymous Online Contributor
"The common treatments for lung diseases include avoidance of smoking, use of bronchodilators and anti-histamines. If the cause of the condition is confirmed, treatment may be tailored according to the cause. There is limited evidence of benefit for alternative treatments." - Anonymous Online Contributor
"Lung disease can be strongly reduced with appropriate treatment, but not completely cured (symptom-free) in most cases. However, due to better anti-inflammatory treatment options and new treatment approaches, the risks of lung disease complications are getting diminished." - Anonymous Online Contributor
"There exists an urgent need to reduce the risk of chronic obstructive pulmonary diseases, in particular COPD, by identifying causes and risk factors and implementing preventive and disease management measures." - Anonymous Online Contributor
"Lung diseases are associated with chest pain, shortness of breath, dizziness, and cough. A chest CT scan may be useful to help determine the disease." - Anonymous Online Contributor
"Of the 33 most common lung diseases in the United States, 14 causes (42%) are associated with significant disease burden. Chronic obstructive pulmonary disease, bronchitis, acute bronchitis, pneumonia, and asthma made up about half of these. Lung diseases are a leading cause of hospitalizations in US; this burden is even greater in the frail elderly and those with other co-morbidities." - Anonymous Online Contributor
"The current study provides evidence of a genetic aetiology associated with pulmonary complications in a relatively homogeneous population of non-responders. We identified a distinct pattern of family aggregation and suggestive linkage." - Anonymous Online Contributor
"aet improves physical functioning as well as quality of life. The improvement of quality of life may be useful to allow patients to achieve a better level of activity, thus increasing their fitness and therefore preventing physical complications, such as cardiovascular disease, pulmonary disorders (symptom relief), and osteoporosis." - Anonymous Online Contributor
"The majority of doctors and patients would not consider a lung disease to be a target for clinical trials even though evidence from clinical trials suggests that some conditions have a positive outcome if treated with medication. However, only a small minority of patients would consider themselves to be research participants in any form of trial of lung diseases." - Anonymous Online Contributor
"Lung diseases are the leading cause of morbidity and mortality in the United States. A multifactorial perspective is important to identify their causal basis so that we can develop lung disease-specific preventive, diagnostic and treatment strategies. The epidemiology of lung diseases is complex and a combination of shared and unique determinants is expected to explain disease patterns." - Anonymous Online Contributor
"Despite a wide range of responses to aet, most studies have found improvements in cardio-respiratory fitness in COPD patients when training is combined with medication. Exercise testing is necessary to assess exercise capacity so the optimum exercise training intensity for patients with COPD is yet to be determined." - Anonymous Online Contributor
"Data from a recent study do not support the opinion that aet is a risk factor for the development of an increased risk of any event other than infection, or that it increases the risk of cancer or cardiac events. This conclusion is based on a review of 1,088 participants in 14 clinical trials which included a total of over 23,600 participants (average 5-year follow-up)." - Anonymous Online Contributor