← Back to Search

Hormone Therapy

obese subjects for Insulin Resistance

N/A
Waitlist Available
Led By Paresh Dandona, MBBS
Research Sponsored by Kaleida Health
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24 hours
Awards & highlights

Study Summary

This study will help us understand the possible beneficial effects of insulin in inflammation. Inflamamtion is considered to be the cause of atherosclerosis and heart disease.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
The Suppression of Toll Like receptors by Insulin
Secondary outcome measures
TLR expression

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: obese type 2 diabetes subjectsExperimental Treatment3 Interventions
obese (BMI >30Kg/m2) subjects with type 2 diabetes infused with insulin dextrose or saline 1 week apart. Each infusion will continue for up to 14 hr
Group II: obese subjectsExperimental Treatment3 Interventions
obese (BMI >30Kg/m2) subjects infused with insulin dextrose or saline 1 week apart. Each infusion will continue for up to 14 hr
Group III: Normal weight subjectsActive Control3 Interventions
Normal weight subjects infused with insulin dextrose or saline 1 week apart. Each infusion will continue for up to 14 hr
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
insulin infusion
2008
Completed Phase 4
~140
Saline Infusion
2008
N/A
~30
Dextrose infusion
2008
N/A
~30

Find a Location

Who is running the clinical trial?

Kaleida HealthLead Sponsor
12 Previous Clinical Trials
1,368 Total Patients Enrolled
2 Trials studying Insulin Resistance
55 Patients Enrolled for Insulin Resistance
University at BuffaloLead Sponsor
131 Previous Clinical Trials
98,929 Total Patients Enrolled
2 Trials studying Insulin Resistance
55 Patients Enrolled for Insulin Resistance
American Diabetes AssociationOTHER
137 Previous Clinical Trials
99,472 Total Patients Enrolled
19 Trials studying Insulin Resistance
982 Patients Enrolled for Insulin Resistance

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
The Suppression of Toll Like Receptors by Insulin
Paresh Dandona 2008. "The Suppression of Toll Like Receptors by Insulin". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01151605.
~2 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top