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General Anesthetic

Propofol slow administration for Low Blood Pressure

Phase 3
Recruiting
Led By Tanaya Sparkle
Research Sponsored by University of Toledo
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
any patient from 18 till 80 years of age
patient undergoing non-cardiac elective surgery
Timeline
Screening 3 weeks
Treatment Varies
Follow Up immediate post-op to 30 days post operatively
Awards & highlights

Study Summary

This trial is testing whether giving propofol more slowly causes fewer problems with blood pressure than the standard way it's given.

Eligible Conditions
  • Low Blood Pressure

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~immediate post-op to 30 days post operatively
This trial's timeline: 3 weeks for screening, Varies for treatment, and immediate post-op to 30 days post operatively for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Patients administered Propofol at a slower rate of infusion will have lower incidence of post induction hypotension than patients administered Propofol at FDA approved rate.
Secondary outcome measures
Patients administered Propofol at a slower rate will have less complications during the early post-op period than patients administered Propofol at FDA approved rate.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Group B- propofol given over 120 secondsExperimental Treatment1 Intervention
Group II: Group A- propofol given at FDA approved administration speedActive Control1 Intervention

Find a Location

Who is running the clinical trial?

University of ToledoLead Sponsor
7 Previous Clinical Trials
642 Total Patients Enrolled
Tanaya SparklePrincipal InvestigatorUniversity of Toledo
Nitin GoyalPrincipal InvestigatorUniversity of Toledo

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this research study allow for individuals over 35 years old to participate?

"This study is currently looking for individuals that fall between 18 and 80 years old."

Answered by AI

What is the long-term outlook for people who receive Propofol slowly?

"There is some efficacy data and multiple rounds of safety data, meaning that Propofol slow administration can be classified as a 3 on the Power team's 1-3 scale."

Answered by AI

What is the maximum patient quota for this research project?

"That is correct. According to the information available on clinicaltrials.gov, this trial is still recruiting patients. The study was originally posted on August 11th, 2022 and was last edited on November 2nd, 2022. They are hoping to enrol 100 patients at a single site."

Answered by AI

Are there any unfilled positions in this trial that patients could sign up for?

"From what is available on clinicaltrials.gov, this trial is currently looking for participants. The 8/11/2022 date refers to when the study was originally posted, with the 11/2/2022 date being when the listing was last edited."

Answered by AI

Who else is applying?

What site did they apply to?
The University of Toledo Medical Center
What portion of applicants met pre-screening criteria?
Did not meet criteria
~39 spots leftby Mar 2025