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Diuretic

Chlorthalidone for High Blood Pressure (DCP Trial)

Phase 3
Waitlist Available
Research Sponsored by VA Office of Research and Development
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up randomization to time to event; average follow-up 3 years
Awards & highlights

DCP Trial Summary

This trial will compare the effects of two different types of medication used to treat high blood pressure in veterans over the age of 65.

DCP Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~randomization to time to event; average follow-up 3 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and randomization to time to event; average follow-up 3 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Time to major cardiovascular event
Secondary outcome measures
All Deaths
Any revascularization of any artery
Erectile dysfunction (ED)
+4 more

DCP Trial Design

2Treatment groups
Active Control
Group I: ChlorthalidoneActive Control1 Intervention
Chlorthalidone daily dose of 25 mg or 12.5 mg for duration of study
Group II: HydrochlorothiazideActive Control1 Intervention
Hydrochlorothiazide daily dose of 50 mg or 25 mg for duration of study

Find a Location

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor
1,608 Previous Clinical Trials
3,293,009 Total Patients Enrolled
William C Cushman, MDStudy ChairMemphis VA Medical Center, Memphis, TN
Areef Ishani, MD MSStudy ChairMinneapolis VA Health Care System, Minneapolis, MN
1 Previous Clinical Trials
2,540 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Have Hydrochlorothiazide's benefits been recognized by the FDA?

"Hydrochlorothiazide received a safety rating of 3 from our team at Power. This is due to the fact that it is a Phase 3 trial, which means there is both data supporting its efficacy as well as multiple rounds of data affirming its safety."

Answered by AI

What are some common conditions that Hydrochlorothiazide is used to alleviate?

"Hydrochlorothiazide is most often used to address edema, but it can also help patients who have suffered a cerebrovascular accident or have kidney diseases. This medication can also be taken preventatively before certain therapeutic procedures."

Answered by AI

Could you tell me if Hydrochlorothiazide has been used in other research projects?

"Hydrochlorothiazide was originally researched in 2015 at UT Southwestern Medical Center. So far, 276 clinical trials have completed and there are 16 more ongoing studies. A significant amount of these investigations are taking place in Indianapolis, Indiana."

Answered by AI

At how many different locations is this experiment being conducted?

"63 clinical sites are participating in this trial, which include locations in major cities such as Indianapolis, North Chicago and Birmingham. However, there are also many other opportunities to participate at smaller medical centres. Keep in mind that if you decide to take part in this study, it may be more convenient to choose a location near you to avoid extensive travel."

Answered by AI

How many people are currently participating in this clinical trial?

"Patient recruitment for this trial has concluded. The study was first posted on June 15th, 2016 and updated April 21st, 2022. There are 784 other trials related to hypertension currently accepting patients as well as 16 clinical trials testing Hydrochlorothiazide that have open enrollment."

Answered by AI

Are people still able to sign up for this experiment?

"As of April 21st, 2022, this clinical trial is no longer looking for new patients to enroll. The study was first posted on June 15th, 2016. If you are interested in other studies, 784 trials for hypertension and 16 for Hydrochlorothiazide are still recruiting participants."

Answered by AI
Recent research and studies
~1531 spots leftby Apr 2025