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Local Anesthetic

Multimodal Pharmacological Management for Pain

Phase 3
Recruiting
Led By Eman Nada, MD
Research Sponsored by Eman Nada
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Adult Patients undergoing lumbar spinal fusion surgery.
Patients from 40-80 years.
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 48ours
Awards & highlights

Study Summary

This trial will compare two local anesthetic blocks in different locations for postoperative pain control after lumbar spinal fusion, to see if it reduces opioid use.

Eligible Conditions
  • Pain
  • Opioid Use Disorder
  • Slipped Disc

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~48ours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 48ours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Opioid Consumption
Secondary outcome measures
Discharge Opioid Use
Pain Scale
Side Effects

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Group 2 Standard of Care + Quadratus Lumborum Block IIIExperimental Treatment2 Interventions
Group III will receive standard of care multimodal pharmacological management plus the Quadratus Lumborum III local anesthetic block. We will measure opioid use, pain, and side effects in each patient.
Group II: Group 2 Standard of Care + Quadratus Lumborum Block IIExperimental Treatment2 Interventions
Group II will receive standard of care multimodal pharmacological management plus the Quadratus Lumborum II local anesthetic block.
Group III: Group 1 Standard of CareActive Control1 Intervention
Group I will receive the standard of care multimodal pharmacological management.

Find a Location

Who is running the clinical trial?

Eman NadaLead Sponsor
Eman Nada, MDPrincipal Investigator - University of Massachusetts, Worcester
UMass Memorial Medical Center-University Campus

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this clinical trial only available to patients who are under 30 years old?

"In order to be included in this particular trial, patients must be between 40 and 80 years old. Out of the 838 total clinical trials, this is one of the 133 that focuses on a younger demographic and one of the 705 that focuses on an older demographic."

Answered by AI

Are we still welcoming people who want to participate in this research?

"That is correct, the listing on clinicaltrials.gov does show that the research team is actively looking for participants. The trial was first advertised on December first 2020 and was most recently updated on March 18th 2021. They are currently trying to enrol 30 individuals at a single site."

Answered by AI

What does Multimodal Pharmacological Management usually address?

"Multimodal Pharmacological Management is a standard course of treatment for cervical syndrome. It is also effective in treating conditions such as minor burns, labour, and transplantation."

Answered by AI

Are there other examples where doctors have used multiple drugs to manage a condition?

"202 ongoing studies for Multimodal Pharmacological Management exist as of now, with 49 in Phase 3. Most clinical trials for this topic are situated in Duarte, CA, but there are 1196 locations running similar trials."

Answered by AI

Has the FDA acknowledged the benefits of Multimodal Pharmacological Management?

"The safety of Multimodal Pharmacological Management has been well-documented in Phase 3 trials, leading our team to rate it a 3 on our safety scale."

Answered by AI
~7 spots leftby Mar 2025