Community-Based, Client-Centered Prevention Home for Reduction, Harm

Phase-Based Progress Estimates
2
Effectiveness
3
Safety
Reduction, Harm+6 More
Community-Based, Client-Centered Prevention Home - Other
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test if a 12-week intensive multilevel harm reduction case-management intervention can help reduce risky behaviors and lower infectious disease risks in people who inject drugs.

Eligible Conditions
  • Reduction, Harm
  • Hepatitis C
  • Opioid Use Disorder (OUD)
  • Drug Use Disorders

Treatment Effectiveness

Effectiveness Progress

2 of 3
This is further along than 85% of similar trials

Study Objectives

8 Primary · 2 Secondary · Reporting Duration: Year 2

Month 6
Social stigmata
Change in smoking frequency as assessed by self-reported behaviors
Change in the addiction treatment accessibility and utilization as assessed by change in Likert scale
Change in the addiction treatment accessibility and utilization as assessed by change in frequency of "Yes" answers
Change in the risk of HIV as assessed by change in Likert scale
HIV
Change in the risk of drug overdose as assessed by change in Likert scale
Narcan
Change in the risk of viral hepatitis as assessed by change in Likert scale
Change in the treatment frequency of viral hepatitis as assessed by Wisconsin(WI) surveillance databases and Medicaid data.
Year 2
Addiction treatment accessibility and utilization frequency assessment from long term Medicaid data.
Hepatitis C treatment frequency from long term Medicaid data.

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Trial Design

3 Treatment Groups

Nonintervention
1 of 3
Delayed Intervention
1 of 3
Immediate Intervention
1 of 3
Active Control
Experimental Treatment

405 Total Participants · 3 Treatment Groups

Primary Treatment: Community-Based, Client-Centered Prevention Home · No Placebo Group · Phase 3

Delayed Intervention
Other
Experimental Group · 1 Intervention: Community-Based, Client-Centered Prevention Home · Intervention Types: Other
Immediate Intervention
Other
Experimental Group · 1 Intervention: Community-Based, Client-Centered Prevention Home · Intervention Types: Other
NoninterventionNoIntervention Group · 1 Intervention: Nonintervention · Intervention Types:

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: year 2

Who is running the clinical trial?

Tulane UniversityOTHER
94 Previous Clinical Trials
227,956 Total Patients Enrolled
University of Wisconsin, MadisonLead Sponsor
1,061 Previous Clinical Trials
2,563,394 Total Patients Enrolled
National Institute on Drug Abuse (NIDA)NIH
2,225 Previous Clinical Trials
5,612,522 Total Patients Enrolled
Ryan Westergaard, MD, PhD, MPHPrincipal InvestigatorUniversity of Wisconsin, Madison
2 Previous Clinical Trials
428 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 2 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
The text states that someone who has injected drugs in the past 30 days and resides in Wisconsin is over 18 years of age.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 25th, 2021

Last Reviewed: October 13th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.