← Back to Search

Procedure

Photodynamic Therapy for Head and Neck Cancer

Phase 2
Waitlist Available
Research Sponsored by Quintiles, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Histologically confirmed recurrent, refractory, or second primary squamous cell cancer of the head and neck that is incurable with surgery or radiotherapy
Locally accessible, discrete tumor(s) by CT or MRI scan
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Study Summary

This trial is studying how well photodynamic therapy works in treating patients with head and neck cancer.

Who is the study for?
This trial is for adults with recurrent, refractory, or second primary squamous cell cancer of the head and neck that can't be cured by surgery or radiation. Candidates must have tumors visible on CT/MRI scans and not suitable for anesthesia or reconstructive surgery. Excluded are pregnant/nursing individuals, those who've had recent experimental drugs/surgery/radiation, and people with diseases worsened by light.Check my eligibility
What is being tested?
The study tests photodynamic therapy as a palliative treatment for head and neck cancer. This involves using a drug that makes cancer cells sensitive to light followed by exposure to specific lights intended to destroy the tumor cells.See study design
What are the potential side effects?
Potential side effects include skin sensitivity to light (photosensitivity), which may cause burns if exposed to bright light too soon after treatment; swelling around the treated area; pain; scarring; changes in skin pigmentation.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check β€œYes” for the criteria below
Select...
My head or neck cancer cannot be cured with surgery or radiation.
Select...
My tumor can be seen and measured on a CT or MRI scan.
Select...
I am over 18 years old.
Select...
I can care for myself but may not be able to do active work.
Select...
It has been over a month since my last surgery and I have recovered.
Select...
I do not have any conditions worsened by light exposure.
Select...
I have not undergone photodynamic therapy.
Select...
My cancer cannot be cured with surgery or radiation due to its advanced stage.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Find a Location

Who is running the clinical trial?

Quintiles, Inc.Lead Sponsor
160 Previous Clinical Trials
115,086 Total Patients Enrolled
Barbara LarsonStudy ChairQuintiles, Inc.

Media Library

Photodynamic Therapy (Procedure) Clinical Trial Eligibility Overview. Trial Name: NCT00003856 β€” Phase 2
Photodynamic Therapy (Procedure) 2023 Treatment Timeline for Medical Study. Trial Name: NCT00003856 β€” Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has this treatment been officially sanctioned by the FDA?

"As this is a Phase 2 trial, there exists evidence of safety but none for efficacy. Therefore, the Power team gave it a rating of two on their scale from 1 to 3."

Answered by AI

Could you provide an estimate of the number of clinical institutions that are currently participating in this experiment?

"At present, seven medical sites are enrolling in this trial. These clinics can be found in Little Rock, New york and Evanston amongst others - it is advised to select the nearest one if you choose to take part, so as to reduce travel commitments."

Answered by AI

Are any new participants being admitted to this trial?

"As indicated on clinicaltrials.gov, this medical experiment has ceased recruiting new patients since its last update on December 18th 2013. It was originally posted October 1st 1998. Although it is not currently enrolling participants, there are 481 other active studies that interested individuals can look into instead."

Answered by AI
~3 spots leftby Mar 2025