This trial will study the drug OMS721 in patients with IgA nephropathy to see if it is safe and effective. The study will look at how much protein is in the urine after 36 weeks of treatment.
- Immunoglobulin A Nephropathy
1 Primary · 4 Secondary · Reporting Duration: 168 Weeks
2 Treatment Groups
1 of 2
1 of 2
450 Total Participants · 2 Treatment Groups
Primary Treatment: OMS721 · Has Placebo Group · Phase 3
Who is running the clinical trial?
Age 18+ · All Participants · 5 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Who else is applying?
What state do they live in?
What site did they apply to?
|Omeros Investigational Site||100.0%|
What portion of applicants met pre-screening criteria?
- Reich, Heather N., and Jürgen Floege. 2022. “How I Treat Iga Nephropathy”. Clinical Journal of the American Society of Nephrology. American Society of Nephrology (ASN). doi:10.2215/cjn.02710322.
- Reich HN, Floege J. How I Treat IgA Nephropathy. Clin J Am Soc Nephrol. 2022 Aug;17(8):1243-1246. doi: 10.2215/CJN.02710322. Epub 2022 Jun 8. No abstract available.
- 2018. "Study of the Safety and Efficacy of OMS721 in Patients With Immunoglobulin A (IgA) Nephropathy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03608033.
Frequently Asked Questions
Have other research teams attempted anything like this previously?
"Currently, there are 2 ongoing studies for OMS721 across 10 countries and 45 cities. The earliest study was completed in 2018 by 450 participants.Sponsored by Omeros Corporation, this trial reached Phase 3 drug approval and 1 more trials have been conducted since then." - Anonymous Online Contributor
What is the maximum number of patients who can enroll in this trial?
"That is correct. The information available on clinicaltrials.gov reveals that this particular trial is still recruiting patients. This specific study was originally posted on February 16th, 2018 and was most recently updated on May 28th, 2019. In total, they are looking for 450 participants spread out over 21 different locations." - Anonymous Online Contributor
Are researchers actively seeking participants for this trial?
"That is correct, the information available on clinicaltrials.gov reveals that this particular trial is looking for new patients. This specific trial was created on 2/16/2018 and updated as recently as 5/28/2019. In total, they are seeking 450 participants from 21 different locations." - Anonymous Online Contributor
Are there several sites running this trial in the city?
"To make things as convenient as possible for the patients, this clinical trial is enrolling at 21 locations. These medical centres are situated in Albuquerque, Minneapolis, Columbus and 18 other cities. Consequently, when deciding whether or not to participate, please consider how close the sites are to your residence." - Anonymous Online Contributor
Are there any life-threatening risks associated with OMS721?
"OMS721 is in Phase 3 of clinical trials, so there is some data supporting efficacy and multiple rounds of data supporting safety." - Anonymous Online Contributor
What is the history of research on OMS721?
"There are two ongoing clinical trials researching the efficacy of OMS721. One of these live studies is in Phase 3. The majority of research for this treatment is being conducted in Vilnius and Washington, but there are 60 total locations running trials." - Anonymous Online Contributor