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Contact Lens

OrthoK Lenses for Myopia Progression

Phase 2
Waitlist Available
Research Sponsored by Illinois College of Optometry
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights

Study Summary

This trial is investigating whether orthokeratology (ortho-k) lenses, which are worn at night and change the corneal topography to correct low to moderate amounts of myopia, can also help slow axial elongation (which leads to degenerative changes like retinal detachment, glaucoma, and vitreal degeneration) in young adults.

Who is the study for?
This trial is for young adults aged 21-30 who are first-year optometry students with mild to moderate nearsightedness (myopia) and no serious eye conditions. Participants must be able to sleep at least six hours nightly, have good overall health, and commit to all necessary follow-up appointments.Check my eligibility
What is being tested?
The study tests if wearing orthokeratology (ortho-k) lenses at night can slow down the worsening of myopia in young adults. These specialty lenses reshape the cornea temporarily to correct vision.See study design
What are the potential side effects?
Potential side effects from using ortho-k lenses include discomfort or irritation in the eyes, risk of infection, temporary visual disturbances like glare or halos, especially when adapting to lens wear.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Myopia Progression

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: OrthoKExperimental Treatment1 Intervention
OrthoK lenses will be prescribed for subjects randomly and followed for 2yrs throughout wearing the lenses. There will be an enrollment appointment, dispense appointment, 1-day, 1-week, 1-month, 6-month, 12-month, and 24-month follow-ups.
Group II: ControlPlacebo Group1 Intervention
Subjects in the randomly assigned control will continue to wear their glasses throughout the 2yr follow-up period. There will be an enrollment appointment, 6-month, 12-month, and 24-month follow-ups.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
OrthoK
2017
N/A
~50

Find a Location

Who is running the clinical trial?

Illinois College of OptometryLead Sponsor
6 Previous Clinical Trials
272 Total Patients Enrolled
2 Trials studying Myopia
115 Patients Enrolled for Myopia

Media Library

OrthoK (Contact Lens) Clinical Trial Eligibility Overview. Trial Name: NCT02623543 — Phase 2
Myopia Research Study Groups: Control, OrthoK
Myopia Clinical Trial 2023: OrthoK Highlights & Side Effects. Trial Name: NCT02623543 — Phase 2
OrthoK (Contact Lens) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02623543 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the eligibility requirements to participate in this trial?

"Candidates aged between 20 and 40, who have experienced disease progression, can qualify for this trial. In total, 80 individuals are expected to be enrolled."

Answered by AI

How perilous is OrthoK for individuals?

"Based on our research at Power, OrthoK was given a rating of 2 since the intervention is in Phase 2. This implies there has been some evidence demonstrating its safety profile but no data confirming efficacy."

Answered by AI

Are there still opportunities for individuals to participate in this research?

"The given clinical trial does not appear to be currently enrolling patients, as the last update was made on December 3rd 2015. Despite this, there are still 74 other trials that require volunteers at this time."

Answered by AI

Is the age criterion for this experiment restricted to individuals over 25 years of age?

"Per the requirements of this clinical trial, potential participants must range between 20 and 40 years old."

Answered by AI
~7 spots leftby Mar 2025