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ER Beta Agonist for Depression
Study Summary
This trial is testing the safety and efficacy of a drug to treat depression in women who have previously responded to estrogen therapy.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I do not have a major psychiatric illness or serious sleep disorder.I have had heart disease, blood clots in my lungs, or vein inflammation.I am not on medication, except possibly for menopause, thyroid issues, occasional pain, or allergies.I have kidney, liver issues, gallbladder inflammation, or high blood pressure.I have had breast cancer or an unexamined breast lump.I have a history of uterine cancer or unexplained issues in my pelvic area.I am not pregnant and will use barrier methods of contraception if sexually active.I have felt unhappy or uncomfortable due to hormone replacement therapy.I have had a stroke.I had depression linked to perimenopause in the last 12 years, which improved with hormone therapy.I am a woman aged between 45 and 65.I have had major depression with thoughts of suicide in the past.I am capable of understanding and consenting to participate.I frequently experience migraine headaches.
- Group 1: Arm 1
- Group 2: Arm 3
- Group 3: Arm 2
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Could you please inform me about the risks associated with ER beta agonist?
"ER beta agonist is a medication that showed some promise in early stages of testing, but has not been proven effective. Power rates the safety of this drug as a 2."
Which kind of patient would be most likely to benefit from enrolling in this clinical trial?
"This study, which is looking for 54 participants that suffer from depression, has certain age and medication criteria. Patients must be between 45 and 65 years old and not currently taking any mood stabilizers or sleep medications with a few exceptions (e.g. women who have discontinued menopausal hormone therapy within the 12 years prior to the study). In addition, all potential patients must have completed the screening protocol #88-M-0131 during which they will have received psychiatric, medical, and reproductive evaluations to confirm good health. Lastly, potential subjects must be of consenting age."
Can people still sign up for the trial?
"The clinicaltrials.gov website indicates that this study is still enrolling patients. The listing was created on May 23rd, 2019 and was last updated on July 6th, 2022."
Are researchers seeking test subjects who are 18 years of age or older for this experiment?
"Eligibility for this study is restricted to those aged 45 to 65. Out of the 1,202 total studies, 205 are for people under 18 and 997 are for seniors."
How many people does this research project have the capacity to help?
"According to the latest information on clinicaltrials.gov, this study is still recruiting patients. This particular trial was posted on 5/23/2019 and last updated on 7/6/2022. They are looking for 54 individuals who meet the criteria and live near the 1 location."
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