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BMS-986207 for Non-Small Cell Lung Cancer

Phase 2
Waitlist Available
Research Sponsored by Bristol-Myers Squibb
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up from randomization to time of death, 2.3 months
Awards & highlights

Summary

This trial will test a new cancer treatment involving a combination of drugs. The goal is to see if it is safe and effective for people with stage IV non-small cell lung cancer.

Eligible Conditions
  • Non-Small Cell Lung Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from randomization to time of death, 2.3 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and from randomization to time of death, 2.3 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Progression Free Survival by BICR
Secondary study objectives
Duration of Response (DOR) by Investigator
Overall Response Rate (ORR) by BICR
Overall Response Rate (ORR) by Investigator
+2 more

Side effects data

From 2022 Phase 2 trial • 1 Patients • NCT05005273
100%
Cardiac arrest
100%
Sepsis
100%
Bronchitis
100%
Blood alkaline phosphatase increased
100%
Blood lactate dehydrogenase increased
100%
Hypoalbuminaemia
100%
Hypokalaemia
100%
Nausea
100%
Hyponatraemia
100%
Eczema
100%
80%
60%
40%
20%
0%
Study treatment Arm
Nivolumab 360 mg + Ipilimumab 1 mg/kg + Placebo
Nivolumab 360 mg + Ipilimumab 1 mg/kg + BMS-986207 600 mg

Trial Design

2Treatment groups
Experimental Treatment
Group I: Arm BExperimental Treatment3 Interventions
Group II: Arm AExperimental Treatment3 Interventions
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Nivolumab
2014
Completed Phase 3
~5220
Ipilimumab
2014
Completed Phase 3
~3140
BMS-986207
2022
Completed Phase 2
~110

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Who is running the clinical trial?

Bristol-Myers SquibbLead Sponsor
2,679 Previous Clinical Trials
4,125,210 Total Patients Enrolled
~0 spots leftby Oct 2025
Unbiased ResultsWe believe in providing patients with all the options.
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