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Macrolide Antibiotic
Azithromycin for Asthma
Phase 2
Waitlist Available
Led By Steve White, MD
Research Sponsored by University of Chicago
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Currently prescribed ICS + LABA
Smoking history < 10 pack-years
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 8 weeks
Awards & highlights
Study Summary
This study is evaluating whether a common antibiotic may help treat asthma.
Eligible Conditions
- Asthma
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 8 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~8 weeks
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Asthma Control Test (ACT) Score Change From Baseline Over 8 Weeks
Secondary outcome measures
Forced Expiratory Volume (FEV1) Change From Baseline Over 8 Weeks
Microbiome Beta-diversity Score Change From Baseline to 8 Weeks
Microbiome Change in Relative Proportion of Top 10 Genera From Baseline to 8 Weeks
+4 moreTrial Design
3Treatment groups
Active Control
Placebo Group
Group I: Non-asthmatic controlsActive Control1 Intervention
Non-asthmatic controls to assess variability of microbiome composition and diversity over time in a normal population. No intervention given.
Group II: AzithromycinActive Control1 Intervention
8 weeks of Azithromycin (250 mg) capsule once daily by mouth
Group III: PlaceboPlacebo Group1 Intervention
8 weeks of placebo capsule once daily by mouth
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Who is running the clinical trial?
University of ChicagoLead Sponsor
995 Previous Clinical Trials
816,651 Total Patients Enrolled
16 Trials studying Asthma
1,857 Patients Enrolled for Asthma
Northwestern UniversityOTHER
1,576 Previous Clinical Trials
911,905 Total Patients Enrolled
8 Trials studying Asthma
675 Patients Enrolled for Asthma
Steve White, MDPrincipal InvestigatorUniversity of Chicago
Frequently Asked Questions
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