Your session is about to expire
← Back to Search
Study Summary
This trial will investigate if avelumab in combination with talazoparib can treat patients with locally advanced or metastatic solid tumors that have a BRCA or ATM defect.
- Solid Tumors
- BRCA1 (Breast Cancer 1)
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
Find a Location
Who is running the clinical trial?
Frequently Asked Questions
What has been revealed regarding the security of Avelumab for patients?
"Our in-house analysis has rated the safety of avelumab at a 2, as it is currently undergoing Phase 2 trials and there are some encouraging signs regarding its safety profile but insufficient data to prove efficacy."
How many subjects are receiving treatments as part of this clinical trial?
"Unfortunately, this experiment has concluded its recruitment process. Initially posted on June 18th 2018 and last updated September 26h 2022, so no further patients are sought after at present. There are 17 trials seeking individuals with brca 1 genes and 161 studies recruiting for Avelumab treatment respectively."
How many medical facilities are conducting this research project?
"This medical experiment is welcoming participants from 61 different locations, including Northside Hospital-GCS/Macon in Macon, Georgia; The Sarah Cannon Research Institute in Hermitage, Massachusetts; and Brigham and Women's Hospital in Boston, Ohio."
What therapeutic purposes does Avelumab tend to be employed for?
"Avelumab is a viable treatment option for conditions such as advance directives, BRCA1 gene mutations and Merkel cell carcinoma."
Are there still openings available in this research study?
"Unfortunately, per clinicaltrials.gov this study is not currently recruiting patients. It was initially announced on June 18th, 2018 and has been updated most recently on September 26th 2022. Nevertheless, 178 other medical studies are actively seeking participants at the moment."
Are there any published reports about the effectiveness of Avelumab in clinical trials?
"Avelumab was first investigated by City of Hope in 2010, and since then 70 clinical trials have been finished. Currently, 161 more are ongoing with many being conducted out of Macon, Georgia."
Share this study with friends
Copy Link
Messenger