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Custom Dynamic Orthosis

Carbon Fiber Custom Dynamic Orthosis (CDO) for Acute Lymphoblastic Leukemia (PRMRP-Norms Trial)

N/A
Waitlist Available
Led By Jason M Wilken, PT, PhD
Research Sponsored by University of Iowa
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Ability to hop without pain
Ability to perform a full squat without pain
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline
Awards & highlights

PRMRP-Norms Trial Summary

This trial will help researchers understand how different designs of carbon fiber braces can reduce stress on the ankle joint, which will inform future development of braces and other treatments for ankle injuries.

Eligible Conditions
  • Acute Lymphoblastic Leukemia
  • Healthy Subjects

PRMRP-Norms Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You can hop without feeling any pain.
Select...
You can do a full squat without feeling any pain.
Select...
You can move your legs and back without any limitations.

PRMRP-Norms Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Joint Contact Stress-Time Exposure
Secondary outcome measures
Ankle Range of Motion
Four Square Step Test (4SST)
Gastrocnemius Muscle Force (N)
+12 more
Other outcome measures
Center of Pressure Velocity Magnitude
Center of Pressure Velocity Timing
Medial Gastrocnemius Muscle Activity (Electromyography)
+6 more

PRMRP-Norms Trial Design

6Treatment groups
Experimental Treatment
Group I: NoCDO, CDOC, CDOB, CDOAExperimental Treatment1 Intervention
Participants will be evaluated without a CDO, then with CDOC, then with CDOB, then with CDOA.
Group II: NoCDO, CDOC, CDOA, CDOBExperimental Treatment1 Intervention
Participants will be evaluated without a CDO, then with CDOC, then with CDOA, then with CDOB.
Group III: NoCDO, CDOB, CDOC, CDOAExperimental Treatment1 Intervention
Participants will be evaluated without a CDO, then with CDOB, then with CDOC, then with CDOA.
Group IV: NoCDO, CDOB, CDOA, CDOCExperimental Treatment1 Intervention
Participants will be evaluated without a CDO, then with CDOB, then with CDOA, then with CDOC.
Group V: NoCDO, CDOA, CDOC, CDOBExperimental Treatment1 Intervention
Participants will be evaluated without a CDO, then with CDOA, then with CDOC, then with CDOB.
Group VI: NoCDO, CDOA, CDOB, CDOCExperimental Treatment1 Intervention
Participants will be evaluated without a CDO, then with CDOA, then with CDOB, then with CDOC.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Carbon Fiber Custom Dynamic Orthosis (CDO)
2021
N/A
~10

Find a Location

Who is running the clinical trial?

University of IowaLead Sponsor
443 Previous Clinical Trials
878,681 Total Patients Enrolled
Jason M Wilken, PT, PhDPrincipal InvestigatorUniversity of Iowa
10 Previous Clinical Trials
304 Total Patients Enrolled

Media Library

Carbon Fiber Custom Dynamic Orthosis (CDO) (Custom Dynamic Orthosis) Clinical Trial Eligibility Overview. Trial Name: NCT04800510 — N/A
Acute Lymphoblastic Leukemia Research Study Groups: NoCDO, CDOB, CDOA, CDOC, NoCDO, CDOC, CDOB, CDOA, NoCDO, CDOA, CDOB, CDOC, NoCDO, CDOB, CDOC, CDOA, NoCDO, CDOC, CDOA, CDOB, NoCDO, CDOA, CDOC, CDOB
Acute Lymphoblastic Leukemia Clinical Trial 2023: Carbon Fiber Custom Dynamic Orthosis (CDO) Highlights & Side Effects. Trial Name: NCT04800510 — N/A
Carbon Fiber Custom Dynamic Orthosis (CDO) (Custom Dynamic Orthosis) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04800510 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there room for additional participants in this clinical trial?

"Clinicaltrials.gov does not indicate that this trial is currently enrolling patients; the original posting was on April 21st 2021 and it has been updated as recently as July 12th 2022. Nonetheless, there are still 851 other studies actively recruiting individuals at present."

Answered by AI

Am I a suitable participant for this scientific investigation?

"To qualify for this clinical trial, applicants must have no pre-existing health conditions and be between the ages of 18 to 50. About 9 successful candidates are being sought after."

Answered by AI

Does the protocol for this experiment permit individuals of advanced age to participate?

"As outlined in the eligibility criteria, individuals aged 18 to 50 are qualified for participation in this medical study."

Answered by AI
~2 spots leftby Mar 2025