CLINICAL TRIAL

Carbohydrate drink for Glycemic Index

Waitlist Available · 18 - 65 · Male · Phoenix, AZ

GRAPE • Glycemic Response of Amylopectin Containing Drinks

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About the trial for Glycemic Index

Treatment Groups

This trial involves 3 different treatments. Carbohydrate Drink is the primary treatment being studied. Participants will be divided into 2 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Experimental Group 1
Energy smart Carbohydrate blend
DIETARYSUPPLEMENT
Experimental Group 2
Carbohydrate drink
DIETARYSUPPLEMENT
Control Group 3
Liquid Dextrose
DIETARYSUPPLEMENT

About The Treatment

Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Carbohydrate drink
2014
N/A
~20

Eligibility

This trial is for male patients between 18 and 65 years old. There is one eligibility criterion to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
BMI 27.5 to 35 kg∙m-2
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Odds of Eligibility
Unknown<50%
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial

Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: 30, 60 and 120 minutes of the glucose challenge
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: 30, 60 and 120 minutes of the glucose challenge.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Carbohydrate drink will improve 4 primary outcomes and 5 secondary outcomes in patients with Glycemic Index. Measurement will happen over the course of 120 minutes.

Area Under the Curve of Glucose
120 MINUTES
Positive integer of the area under the Curve of glucose
Area Under the Curve for Insulin
120 MINUTES
Positive integer of the area under the Curve of insulin
glucagon
30, 60, AND 120 MINUTES OF OF THE GLUCOSE CHALLENGE
Blood levels of glucagon
glucagon-like-peptide-1
30, 60, AND 120 MINUTES OF THE GLUCOSE CHALLENGE
Blood levels of glucagon-like-peptide-1
c-peptide
30, 60, AND 120 MINUTES OF THE GLUCOSE CHALLENGE
Blood levels of c-peptide
Leptin
30, 60, AND 120 MINUTES OF THE GLUCOSE CHALLENGE
Blood levels of leptin
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Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can glycemic index be cured?

Despite high levels of glycemic index and low compliance, diabetes can be cured, but not reversed, by dietary restriction, exercise alone, or exercise combined with insulin injection.

Anonymous Patient Answer

What is glycemic index?

GI is typically applied as a measure of the glycemic effect of a carbohydrate relative to other carbohydrates consumed. While GI and GL are used interchangeably, GI has been shown consistently to perform better than GL in predicting postprandial blood glucose levels in humans, particularly when consumed with a meal. In studies correlating GI with body weight, the GI is shown to correlate strongly with fasting blood glucose concentrations even with low body weights. GI may therefore be an appropriate surrogate marker for the glycemic load of foods. The GI of foods has been shown to be associated with the rate of insulin resistance, a risk factor for type 2 diabetes.

Anonymous Patient Answer

What are common treatments for glycemic index?

It is very important to ensure that any dietary management that aims to decrease the chance of cardiovascular disease or diabetes mellitus does not affect the chance of developing the other condition, especially in younger people.

Anonymous Patient Answer

How many people get glycemic index a year in the United States?

1.7 million people in America a year have insulin-mediated type 2 DM. 2.2 million people in America a year have undiagnosed prediabetes. 3.8 million people in America a year have undiagnosed type 2 DM. 5.4 million people in America a year are diagnosed with the full presentation of diabetes (diagnosed with type 2 DM and prediabetes, or undiagnosed type 2 DM). 5.4 million people in America a year are diagnosed with the full presentation of prediabetes. 5.4 million people in America a year have undiagnosed prediabetes.

Anonymous Patient Answer

What are the signs of glycemic index?

The glycemic index is the main factor responsible for the variation in patient glycosylated hemoglobin (HbA(1c)) levels following intake of the same amount of carbohydrate; it accounts for 20% of the variation among study patients. The glycemic index deserves further study as a possible target for diabetic control strategies.

Anonymous Patient Answer

What causes glycemic index?

The most likely explanation of the elevated glycemic index seen in persons of European ancestry and type 2 diabetes is a defect in glucose/insulin signaling, manifested possibly by a defect in signal transduction in a tissue that may not necessarily be insulin-sensitive.

Anonymous Patient Answer

What are the latest developments in carbohydrate drink for therapeutic use?

In the last 10-12 years, the consumption of carbohydrate drinks has been changing dramatically. This shift in consumption occurred because customers were dissatisfied with the previously available options of carbohydrate drinks, because they wanted to take an orally administered drug, or because they were wanting to control their weight. In addition, the public was expecting better-tasting and healthier options of dietary supplements and drinks.

Anonymous Patient Answer

What is the latest research for glycemic index?

There's not much research on this topic. The current literature is limited in its design or reporting quality. There also are methodological concerns such as small sample sizes, selection bias and publication bias which need to be acknowledged. The findings of this review may be limited with respect to the research questions.

Anonymous Patient Answer

What are the common side effects of carbohydrate drink?

There is no consensus among health professionals that a carbohydrate beverage will have negative effects on a person as the amount consumed and drinking patterns change over time. Thus, carbohydrate drinks can have a variety of effects on a person’s body and heart function. The effects can be both positive and negative, and it is good practice to seek your doctor's advice before consuming carb beverages to manage diabetes, weight loss and heart health conditions.

Anonymous Patient Answer

Is carbohydrate drink safe for people?

This review summarizes the current evidence regarding the risks and benefits of replacing solid meals with carbohydrate drinks for weight loss in a variety of patient sub-groups. Given the risks of hypoglycemia with carbohydrate supplements compared with solid meals, particularly for type 2 diabetes, our conclusions should not be extrapolated to the general population.

Anonymous Patient Answer

Has carbohydrate drink proven to be more effective than a placebo?

A standardized carbohydrate drink is not more effective than a placebo in improvement of diabetes, metabolic control (glycemic control), or reducing postprandial glycemic response. Although no harmful effects were observed, the data also show that standardized carbohydrate drinks have no effect on the postprandial glycemic response. The data also demonstrate that standardized carbohydrate drinks do not improve metabolic control or the glycemic response.

Anonymous Patient Answer

Does carbohydrate drink improve quality of life for those with glycemic index?

There was no significant impact of carbohydrate drink ingestion on patient HRQOL. Glycemic indexes of carbohydrates did not correlate with the ability to drink them, either alone or with dairy.

Anonymous Patient Answer
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