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Study Summary
This trial is testing if siltuximab is an effective and safe treatment for patients with schizophrenia who also have evidence of increased inflammation. Siltuximab is a recombinant chimeric (human-murine) anti-human interleukin-6 (IL-6) monoclonal antibody that is given as an intravenous infusion.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- You have a history of stomach ulcers, bowel inflammation, cancer, nerve disorders, seizures, or have been exposed to tuberculosis.Your health condition is considered stable according to the doctor's evaluation.You have taken antibiotics within the last two weeks.You have had a previous immune disorder.You have used illegal drugs in the last 30 days.You are currently not taking a medication called clozapine for your mental health.You have been diagnosed with schizophrenia or schizoaffective disorder.
- Group 1: Treatment Group
- Group 2: Control Group
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Who are the qualified participants for this experiment?
"This clinical trial seeks around 30 participants, aged between 18 and 55 years old, who have a diagnosis of schizophrenia."
Are there any antecedent studies that have focused on Treatment Group?
"Presently, 4 active studies are exploring Treatment Group. Of these trials, none have reached Phase 3 yet. Most of the clinical trials for Treatment Group take place in New york City; however there are 6 other sites conducting similar research."
How many volunteers are participating in this experiment?
"Affirmative. According to the information on clinicaltrials.gov, this medical experiment is presently looking for participants and was first listed in May of 2016 with a most recent update in July 2021. The study requires 30 patients to be recruited from one location."
Is this experiment open to participants who are more than thirty years of age?
"The specified age range for this medical trial is 18 to 55. However, there are 137 trials available for minors and 366 trials specifically geared towards seniors."
Are there any opportunities for participants to join this experiment?
"According to information published on clinicaltrials.gov, this medical study is currently accepting participants. This trial was first announced in May 2016 and saw its latest update take place a few months ago - July 2021."
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