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MT-101 for T-Cell Lymphoma (IMAGINE Trial)
IMAGINE Trial Summary
This trial is testing a new cancer treatment made from patients' own blood cells. The cells are modified to target and kill tumor cells, and then infused back into the patient.
- Cell Therapy
- Cutaneous T-Cell Lymphoma
- Peripheral T-Cell Lymphoma
- Mycosis Fungoides
- Adoptive Cell Therapy
IMAGINE Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.IMAGINE Trial Design
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Who is running the clinical trial?
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- You have experienced a severe allergic reaction to penicillin in the past.You have a specific stage of a condition called myelofibrosis, which is categorized as B1 or B2 as explained in the study's instructions.The cancer has spread to the central nervous system.You have had bad reactions or intolerance to leukapheresis, plasmapheresis, or donating blood in the past.You have any sudden illness, like a fever, except if the fever is caused by your tumor.You have received a transplant using someone else's cells in the past.You have had other types of cancer before, but they have been treated or are in complete remission.
- Group 1: Cohort 1 and Cohort 3
- Group 2: Cohort 2 and Cohort 4
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many healthcare facilities are currently hosting this research endeavor?
"Currently, 7 medical centres are running this trial. Locations include Miami, Boston and Denver with 4 other locations scattered around the country. To reduce travel costs it is advised that patients choose a site close to them if they wish to be enrolled in the study."
What is the upper limit of participants for this experiment?
"To successfully complete this trial, 40 qualified individuals must be recruited. Thus far, two of the available locations for participation are Miami Cancer Institute at Baptist Health in Miami, Florida and Dana-Farber/Mass General Brigham Cancer Care in Boston Massachusetts."
Are there still opportunities for individuals to take part in this trial?
"Affirmative. Clinicaltrials.gov evidences that this clinical trial is currently looking for volunteers, as it was first published on December 15th 2021 and recently updated on October 10th 2022. Forty participants need to be recruited from seven different sites."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
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