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Cross-linking plus INTACS for Keratoconus

Phase 2 & 3
Waitlist Available
Led By Ezra Maguen, M.D.
Research Sponsored by Yaron S. Rabinowitz M.D.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
progressive keratoconus or ectasia
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 10 years
Awards & highlights

Study Summary

This study will determine the efficacy of collagen cross linking for progressive keratoconus and ectasia after lasik. It will try and determine which is a more effective treatment: collagen cross linking alone or collagen cross linking combined with Intacs, a treatment which has already been proven to be effective in decreasing corneal curvature in patients with keratoconus.

Eligible Conditions
  • Keratoconus
  • Aneurysm

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check β€œYes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~10 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 10 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Effectiveness of UV-X cross linking to halt progression of keratoconus

Trial Design

2Treatment groups
Active Control
Group I: Cross-linking plus INTACSActive Control1 Intervention
Corneal collagen cross-linking with riboflavin and UVA light plus INTACS
Group II: Cross-linkingActive Control1 Intervention
Corneal collagen cross-linking with riboflavin and UVA light

Find a Location

Who is running the clinical trial?

Yaron S. Rabinowitz M.D.Lead Sponsor
Ezra Maguen, M.D.Principal Investigatoramerican eye institute
Yuri Oleynikov, M.D. PhDPrincipal InvestigatorCornea Genetic Eye Institute

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

What state do they live in?
Nevada
What site did they apply to?
Cornea Eye Institute, 50 North La Cienaga Blvd, #340
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
0

Why did patients apply to this trial?

I havent tried ncomany drugs to help repair vision but I have invested 2k in contact lenses that are still uncomfortable.
PatientReceived 2+ prior treatments

What questions have other patients asked about this trial?

Does the trial compensate?
PatientReceived no prior treatments
~37 spots leftby Mar 2025