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Respirator for Air Pollution (ASPIRE Trial)

N/A
Waitlist Available
Research Sponsored by University Hospitals Cleveland Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 months
Awards & highlights

ASPIRE Trial Summary

This trial found that long-term exposure to PM2.5 air pollution is a leading global risk factor for cardiovascular morbidity and mortality. Wearing an N95 respirator can help prevent clinical events among patients with cardiovascular disease.

ASPIRE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Blood Pressure
Secondary outcome measures
BP/HRV Monitoring
PWV and pulse wave analysis

ASPIRE Trial Design

2Treatment groups
Active Control
Group I: No interventionActive Control1 Intervention
No respirators will be worn by the control group (control limb, n=100)
Group II: RespiratorActive Control1 Intervention
Open label use of N95 respirators (worn outdoors) (active limb, n=100)

Find a Location

Who is running the clinical trial?

University Hospitals Cleveland Medical CenterLead Sponsor
317 Previous Clinical Trials
340,324 Total Patients Enrolled
University of MichiganOTHER
1,782 Previous Clinical Trials
6,364,677 Total Patients Enrolled
1 Trials studying Air Pollution
50 Patients Enrolled for Air Pollution
Peking UniversityOTHER
424 Previous Clinical Trials
1,046,599 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are new participants still being accepted for this research project?

"According to clinicaltrials.gov, this research is actively scouting for participants. It was originally posted on March 22nd 2019 and recently updated on September 16th 2022."

Answered by AI
~5 spots leftby Mar 2025