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Methotrexate for Proliferative Vitreoretinopathy (SIGHT Trial)
SIGHT Trial Summary
This trial is testing whether methotrexate can help improve outcomes for children with retinal detachment caused by a tear.
SIGHT Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2015 Phase 3 trial • 139 Patients • NCT02001987SIGHT Trial Design
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Frequently Asked Questions
Have other investigations been conducted with Methotrexate?
"Currently, 219 ongoing studies are examining the efficacy of Methotrexate with 67 Phase 3 trials. Although many of these research efforts center around New york City, there exist 7698 sites across the world where investigations into this drug are taking place."
Has Methotrexate been granted authorization by the FDA?
"In light of the limited clinical data available to our team at Power, we have assigned Methotrexate a score of 1 on a scale from 1-3. This is due to it being in its first phase trial stage with minimal evidence for efficacy and safety."
What maladies is Methotrexate most commonly employed to combat?
"Methotrexate is normally given to patients with small cell lung cancer, but it has also demonstrated efficacy in treating active pauciarticular juvenile rheumatoid arthritis, head and neck carcinoma, multiple sclerosis."
What is the current sample size of participants for this research project?
"This clinical trial is no longer taking on applicants. It was initially posted April 1st 2021, with the most recent update being March 31st 2021. If you are looking for other studies related to vitreoretinopathy or methotrexate, there are 9 and 219 trials respectively recruiting participants at this time."
Are there any ongoing opportunities to participate in this trial?
"Unfortunately, this trial is currently not recruiting participants. The information posted on 4/1/2021 and last edited on 3/31/2021 details the fact that it's no longer actively seeking patients. That said, there are presently 9 clinical trials searching for individuals with vitreoretinopathy proliferative as well as 219 studies scouting for Methotrexate users."
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