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Cannabis (THC:CBD = ~ 1:1) for Substance Abuse

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Substance Abuse+1 MoreCannabis (THC:CBD = ~ 1:1) - Drug
Eligibility
21 - 53
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test if cannabis has an impact on the pain-relieving and abuse-potential effects of a sub-threshold dose of a common painkiller.

Eligible Conditions
  • Substance Abuse
  • Pain

Treatment Effectiveness

Effectiveness Progress

1 of 3

Similar Trials

1
Active Cannabis
1
Paroxetine and Oxycodone
1
Low THC + High BCP

Study Objectives

2 Primary · 0 Secondary · Reporting Duration: 6 weeks

6 weeks
Cold Pressor Test
Subjective Effects

Trial Safety

Safety Progress

1 of 3

Similar Trials

1
Active Cannabis
1
Paroxetine and Oxycodone
1
Low THC + High BCP

Trial Design

8 Treatment Groups

Cannabis (THC:CBD = ~ 0:1) + Oxycodone
1 of 8
Oxycodone
1 of 8
Cannabis (THC:CBD = ~ 1:1) + Oxycodone
1 of 8
Cannabis (THC:CBD = ~1:0)
1 of 8
Cannabis (THC:CBD = ~1:0) + Oxycodone
1 of 8
Cannabis (THC:CBD = ~ 0:1)
1 of 8
Cannabis (THC:CBD = ~ 1:1)
1 of 8
Placebo
1 of 8

Experimental Treatment

Non-Treatment Group

26 Total Participants · 8 Treatment Groups

Primary Treatment: Cannabis (THC:CBD = ~ 1:1) · Has Placebo Group · Phase 1

Cannabis (THC:CBD = ~ 0:1) + OxycodoneExperimental Group · 2 Interventions: Oxycodone, Cannabis (THC:CBD = ~ 0:1) · Intervention Types: Drug, Drug
OxycodoneExperimental Group · 2 Interventions: Oxycodone, Placebo · Intervention Types: Drug, Drug
Cannabis (THC:CBD = ~ 1:1) + OxycodoneExperimental Group · 2 Interventions: Oxycodone, Cannabis (THC:CBD = ~ 1:1) · Intervention Types: Drug, Drug
Cannabis (THC:CBD = ~1:0)Experimental Group · 2 Interventions: Placebo, Cannabis (THC:CBD = ~ 1:0) · Intervention Types: Drug, Drug
Cannabis (THC:CBD = ~1:0) + OxycodoneExperimental Group · 2 Interventions: Oxycodone, Cannabis (THC:CBD = ~ 1:0) · Intervention Types: Drug, Drug
Cannabis (THC:CBD = ~ 0:1)Experimental Group · 2 Interventions: Placebo, Cannabis (THC:CBD = ~ 0:1) · Intervention Types: Drug, Drug
Cannabis (THC:CBD = ~ 1:1)Experimental Group · 2 Interventions: Placebo, Cannabis (THC:CBD = ~ 1:1) · Intervention Types: Drug, Drug
Placebo
Drug
PlaceboComparator Group · 1 Intervention: Placebo · Intervention Types: Drug
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Oxycodone
FDA approved
Placebo
1995
Completed Phase 3
~2670

Trial Logistics

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 6 weeks

Who is running the clinical trial?

New York State Psychiatric InstituteLead Sponsor
457 Previous Clinical Trials
148,672 Total Patients Enrolled
5 Trials studying Substance Abuse
1,115 Patients Enrolled for Substance Abuse
Caroline A Cooper, PhDPrincipal InvestigatorNew York Psychiatric Institute

Eligibility Criteria

Age 21 - 53 · All Participants · 6 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are male or non-pregnant female aged 21-53 years.

Who else is applying?

What state do they live in?
New York100.0%
How old are they?
18 - 65100.0%
What site did they apply to?
New York State Psychiatric Institute100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%
References

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