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Cephalosporin Antibiotic

VNRX-7145 for Pharmacokinetics

Phase 1
Waitlist Available
Research Sponsored by Venatorx Pharmaceuticals, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 0-120 hours post dose
Awards & highlights

Study Summary

This trial will study the effects of a new drug on different types of kidney patients.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~0-120 hours post dose
This trial's timeline: 3 weeks for screening, Varies for treatment, and 0-120 hours post dose for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
AUC0-inf
Cmax
Number of subjects with adverse events

Trial Design

5Treatment groups
Experimental Treatment
Group I: Group 5 - End Stage Renal DiseaseExperimental Treatment2 Interventions
End Stage Renal Disease undergoing chronic intermittent hemodialysis
Group II: Group 4 - Severe Renal ImpairmentExperimental Treatment2 Interventions
Severe Renal Impairment
Group III: Group 3 - Moderate Renal ImpairmentExperimental Treatment2 Interventions
Moderate Renal Impairment
Group IV: Group 2 - Mild Renal ImpairmentExperimental Treatment2 Interventions
Mild Renal Impairment
Group V: Group 1 - ControlExperimental Treatment2 Interventions
Healthy control participants will be matched by gender, age, and BMI to participants with renal impairment
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
VNRX-7145
2020
Completed Phase 1
~200
Ceftibuten
2022
Completed Phase 1
~60

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Venatorx Pharmaceuticals, Inc.Lead Sponsor
12 Previous Clinical Trials
1,414 Total Patients Enrolled
2 Trials studying Pharmacokinetics
57 Patients Enrolled for Pharmacokinetics
National Institute of Allergy and Infectious Diseases (NIAID)NIH
3,261 Previous Clinical Trials
5,482,974 Total Patients Enrolled
2 Trials studying Pharmacokinetics
61 Patients Enrolled for Pharmacokinetics

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this trial encompass participants aged 85 years or older?

"Consistent with this clinical trial's selection criteria, the minimum age for participation is 18 and the oldest accepted patient can be up to 82."

Answered by AI

What is the ideal demographic for enrollment in this medical experiment?

"For this clinical trial, 32 individuals aged 18-82 with specific pharmacokinetic profiles are necessary. In order to apply for the study, applicants must be healthy adults in the specified age range and have a BMI between 18.5-40 kg/m2 that matches participants with renal impairment of similar gender, age, and body mass index (BMI). Additionally, males or non-pregnant females can also participate in the research study."

Answered by AI

Are there available spots for patients to join this research endeavor?

"Affirmative. Clinicaltrials.gov's data reveals that this medical trial, which debuted on October 12th 2022, is presently open for recruitment. A total of 32 candidates need to be sourced from 3 separate health centres."

Answered by AI

Have the regulatory authorities given their seal of approval to VNRX-7145?

"The safety of VNRX-7145 was rated a 1 on our team's scale, as this is only at the initial phase of testing with limited corroborating evidence supporting its efficacy and protection."

Answered by AI

What is the upper limit of participants in this research endeavor?

"Indeed, clinicaltrials.gov confirms that this medical investigation is actively seeking participants ever since it was published on October 12th 2022 and its most recent update taking place on November 17th 2022. The research requires 32 volunteers from 3 different hospitals to be enrolled in the trial."

Answered by AI
~13 spots leftby Mar 2025