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Part A: VX-708 (Cohort A1-A3) for Pain
Study Summary
The purpose of this study is to evaluate the safety, pharmacokinetics, and pharmacodynamics of multiple ascending doses of VX-708 in healthy participants
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Logistics
Participation is compensated
You will be compensated for participating in this trial.
Who is running the clinical trial?
Frequently Asked Questions
What criteria must participants meet to qualify for this medical trial?
"This medical trial is taking on 54 participants aged 18 to 55 suffering from pain. The following prerequisites must be met in order for an individual to qualify: BMI of 18.0 - 32.0 kg/m^2, gender not capable of childbearing, and total body weight higher than 50kg."
Are there opportunities for individuals to participate in this trial at present?
"Affirmative. According to data on clinicaltrials.gov, the trial which was initially posted on 17th September 2022 is recruiting participants at this moment in time. 54 volunteers are needed from a single medical site for the research endeavor that was last modified 7 October 2022."
What risks might be associated with taking Part A: Midazolam With or Without VX-708 (Cohort A4)?
"Our analysis at Power awarded Part A: Midazolam With or Without VX-708 (Cohort A4) a score of 1 due to the fact that this is merely a Phase 1 trial, which implies limited data confirming its safety and efficacy."
Are individuals aged 80 or younger able to participate in this medical experiment?
"This clinical trial seeks participants aged 18 years old or older and 55 years old or younger."
To what extent is participation sought in this medical experiment?
"Indeed, the clinicaltrials.gov database has evidence that this research project is actively recruiting participants. It was first posted on September 17th 2022 and was last modified a month later. The investigators are looking for 54 individuals at one site specifically."
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