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Acetylcholinesterase Inhibitor

Aricept- A for Vascular Dementia

Phase 1
Waitlist Available
Led By A. M. Barrett, MD
Research Sponsored by Kessler Foundation
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
I am 18 to100 yrs old.
I had one stroke 4 months to 5 yrs ago
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24 weeks
Awards & highlights

Study Summary

This trial will test whether Aricept can help people with memory problems to better remember how to do everyday tasks.

Eligible Conditions
  • Vascular Dementia
  • Memory Loss
  • Stroke

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Primary: To examine whether taking Aricept results in improvement at remembering steps of functional tasks.
Secondary outcome measures
To examine whether taking Aricept and actually performing functional tasks improves memory over that provided by a self-generation strategy.

Trial Design

2Treatment groups
Experimental Treatment
Group I: Aricept- AExperimental Treatment2 Interventions
Half of subjects are randomized to immediate treatment with donepezil 5mg orally daily following baseline testing, with retesting at 12 and 24 weeks.
Group II: A2-12-week waiting periodExperimental Treatment2 Interventions
The remaining nine subjects are randomized to testing followed by a 12-week waiting period. After the 12 week wait, this group of subjects is retested and begins taking donepezil, 5 mg orally daily, with retesting at 24 weeks

Find a Location

Who is running the clinical trial?

Kessler FoundationLead Sponsor
172 Previous Clinical Trials
10,656 Total Patients Enrolled
PfizerIndustry Sponsor
4,556 Previous Clinical Trials
10,907,665 Total Patients Enrolled
A. M. Barrett, MDPrincipal InvestigatorKessler Foundation
2 Previous Clinical Trials
1,110 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~1 spots leftby Mar 2025