← Back to Search

Anti-metabolites

Chemotherapy for Childhood Leukemia, Lymphoma, or Solid Cancers

Phase 1
Waitlist Available
Research Sponsored by Pacira Pharmaceuticals, Inc
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Histologically proven recurrent or refractory leukemia, lymphoma, or other solid tumor that has overt meningeal involvement
Renal: Creatinine less than 1.5 mg/dL
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Study Summary

This trial is testing a new cancer drug to see if it is effective in treating young patients with leukemia, lymphoma, or solid tumors.

Who is the study for?
This trial is for young patients aged 1-21 with recurrent or refractory meningeal leukemia, lymphoma, or solid tumors. They must have a certain level of platelets and normal liver/renal function, not be pregnant/nursing, use contraception if fertile, and have no uncontrolled illnesses except HIV. Patients can't join if they live outside the US, had recent bone marrow transplants or chemotherapy/radiotherapy.Check my eligibility
What is being tested?
The trial is testing liposomal cytarabine's effectiveness in stopping tumor cells from growing in young patients with specific types of cancer affecting the brain and nervous system. It's an early-phase study to see how well this treatment works.See study design
What are the potential side effects?
While not explicitly listed here, common side effects of chemotherapy like liposomal cytarabine may include nausea, vomiting, hair loss, fatigue, increased risk of infection due to low blood cell counts and potential damage to organs such as the liver or kidneys.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
My cancer has returned or is not responding to treatment and has spread to the lining of my brain or spinal cord.
Select...
My kidney function is good, with creatinine below 1.5 mg/dL.
Select...
My liver function tests are within normal limits.
Select...
I am between 1 and 21 years old.
Select...
I am able to get out of my bed or chair and move around.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Find a Location

Who is running the clinical trial?

Pacira Pharmaceuticals, IncLead Sponsor
133 Previous Clinical Trials
13,780 Total Patients Enrolled
John E. Gait, MDStudy ChairPacira Pharmaceuticals, Inc

Media Library

Liposomal Cytarabine (Anti-metabolites) Clinical Trial Eligibility Overview. Trial Name: NCT00003073 — Phase 1
Brain Tumor Research Study Groups:
Brain Tumor Clinical Trial 2023: Liposomal Cytarabine Highlights & Side Effects. Trial Name: NCT00003073 — Phase 1
Liposomal Cytarabine (Anti-metabolites) 2023 Treatment Timeline for Medical Study. Trial Name: NCT00003073 — Phase 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How extensively is this trial being conducted in U.S. healthcare facilities?

"Subjects are being sought from six specific medical facilities, such as the Texas Children's Cancer Center in Houston and University of Texas Southwestern Medical Centre at Dallas. Additionally, Alberta Children's Hospital in Calgary is taking part along with three other sites."

Answered by AI

To whom is this research opportunity available?

"To qualify for this research program, candidates should have a diagnosis of leukemia and be aged 1-21. Approximately 15 participants are needed to complete the trial."

Answered by AI

Has this therapy gained regulatory approval by the FDA?

"Due to the limited amount of evidence supporting efficacy and safety, our team has assigned a score of 1. This is an indication that this trial is in Phase 1."

Answered by AI

Is there currently an opportunity for volunteers to join this trial?

"Clinicaltrials.gov indicates that this trial is no longer actively enrolling patients, as the study was posted on February 1st 1997 and last edited on March 22nd 2010. However, there are currently 5068 other clinical trials still in search of participants."

Answered by AI

Is there an age restriction for participation in this research?

"This clinical trial seeks individuals between the ages of 1 year and 21 years."

Answered by AI
~1 spots leftby Mar 2025