BI 690517 mild hepatic impairment (Child-Pugh A) for Liver Disease

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Orlando Clinical Research Center, Orlando, FLLiver Disease+1 MoreBI 690517 - Drug
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial tests how mild & moderate liver disease affects drug safety, how it's absorbed & how well it's tolerated.

Eligible Conditions
  • Liver Disease
  • Healthy Subjects

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

2 Primary · 1 Secondary · Reporting Duration: Up to 4 days

Up to 4 days
Area under the concentration-time curve of the analyte in plasma over the time interval from 0 extrapolated to infinity (AUC0-∞)
Area under the concentration-time curve of the analyte in plasma over the time interval from 0 to the last quantifiable data point (AUC0-tz)
Maximum measured concentration of the analyte in plasma (Cmax)

Trial Safety

Safety Progress

1 of 3

Trial Design

3 Treatment Groups

BI 690517 mild hepatic impairment (Child-Pugh A)
1 of 3
BI 690517 normal hepatic function
1 of 3
BI 690517 moderate hepatic impairment (Child-Pugh B)
1 of 3

Experimental Treatment

32 Total Participants · 3 Treatment Groups

Primary Treatment: BI 690517 mild hepatic impairment (Child-Pugh A) · No Placebo Group · Phase 1

BI 690517 mild hepatic impairment (Child-Pugh A)
Drug
Experimental Group · 1 Intervention: BI 690517 · Intervention Types: Drug
BI 690517 normal hepatic function
Drug
Experimental Group · 1 Intervention: BI 690517 · Intervention Types: Drug
BI 690517 moderate hepatic impairment (Child-Pugh B)
Drug
Experimental Group · 1 Intervention: BI 690517 · Intervention Types: Drug
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
BI 690517
2017
Completed Phase 1
~290

Trial Logistics

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: up to 4 days

Who is running the clinical trial?

IQVIA global CROUNKNOWN
Boehringer IngelheimLead Sponsor
2,398 Previous Clinical Trials
9,800,976 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 9 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
Your body mass index (BMI) falls between 18.5 and 36.0 kg/m2.

Frequently Asked Questions

How much of a risk does BI 690517 mild hepatic impairment (Child-Pugh A) pose to individuals?

"With limited clinical evidence to support safety and efficacy, BI 690517 received a score of 1 for mild hepatic impairment (Child-Pugh A)." - Anonymous Online Contributor

Unverified Answer

How numerous are the participants of this research endeavor?

"Indeed, the information publicly available from clinicaltrials.gov affirms that recruitment for this study is ongoing. It was originally advertised on February 21st 2023 and has been recently modified on February 27th 2023, with a goal of enrolling 32 subjects between 2 medical centers." - Anonymous Online Contributor

Unverified Answer

Is there still capacity to enroll individuals in this experiment?

"The clinical trial is presently searching for participants, and its most recent iteration was posted on February 27th 2023. Furthermore, the original posting dates back to February 21st of that same year." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.