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Azacitidine for Acute Myeloid Leukemia
Study Summary
This trial will test the safety and best dose of venetoclax when given with or without idarubicin to pediatric patients with acute myeloid leukemia (AML) that did not respond to treatment or has come back after treatment.
- Acute Myeloid Leukemia
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
How is Azacitidine commonly utilized in treatment?
"Azacitidine is often prescribed to treat synovitis, as well as ophthalmia, sympathetic disorder, full blood count deficiencies and induction chemotherapy."
Are minors permitted to participate in the present research study?
"According to the requirements for this experiment, all participants must be between 2 and 20 years of age."
What prior research has been carried out involving Azacitidine?
"Presently, there are 155 Phase 3 trials and 722 active clinical investigations of Azacitidine. While most testing is taking place in Edmonton, Alberta; numerous international locales have established clinical studies for this drug."
Are there currently any vacancies in this research project?
"Correct. Data hosted on clinicaltrials.gov affirms that this trial is still recruiting volunteers, having been posted initially in July 2017 and last updated in late July 2022. A total of 72 patients are needed from 2 different medical institutions."
Who qualifies for inclusion in this clinical trial?
"To qualify for this clinical investigation, prospective participants must have a diagnosis of leukemia and be between 2 to 20 years old. The trial is currently aiming to enrol 72 patients in total."
Does Azacitidine pose any significant risks to users?
"The safety of Azacitidine is tentatively rated at 1, as this Phase 1 trial has only provided a small amount of evidence for both its efficacy and security."
How many participants are currently participating in this investigation?
"Affirmative. Clinicaltrials.gov records show that this investigation, which first appeared online on July 11th 2017, is still recruiting participants as of the last edit made on July 25th 2022. 72 individuals must be recruited from two individual sites for full data collection to occur."
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